Is GLUCOSE safe to use in EU cosmetics?

GLUCOSE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 50-99-7?

CAS 50-99-7 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains GLUCOSE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3401215/10/2010

GLUCOSE

Glucose

GLUCOSE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 50-99-7

CAS 50-99-7PubChem CID 5793

D-Glucose

Watery odorless colorless liquid. Denser than water and soluble in water. Hence sinks in and mixes with water. (USCG, 1999) — CAMEO Chemicals

IUPAC name: (3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol

Molecular formula: C6H12O6
Molecular weight: 180.16 g/mol
Exact mass: 180.06338810 Da
XLogP3: -2.6
Topological polar surface area: 110.0 Å²
Hydrogen-bond donors: 5
Hydrogen-bond acceptors: 6
Covalent units: 1
Defined stereocentres: 4

Also known as

D-GlucopyranoseglucoseGlucopyranoseGrape sugarBlood sugarD-GlcTraubenzuckerGlucosteril

16 more reported names

Cartoseanhydrous glucoseMaxim Energy GelGlucosum, anhydrousStaleydex 333Corn sugard-glucopyranosideGLUCOSE, ALPHA-D-CereloseDextropurDextrosolGlucolinGoldsugarVadexCHEBI:17234CHEBI:17634

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:4167
ChEMBL:CHEMBL1222250
EPA DTXSID:DTXSID501015215
EPA DTXSID:DTXSID901015217
PubMed:35307376
PubMed:35258167
PubMed:35235096
PubMed:35191607
PubMed:34740634
PubMed:34355838
PubMed:34351043
PubMed:34217758
PubMed:34174262
PubMed:34078833
PubMed:33812996
PubMed:33729688

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for GLUCOSE

INCI name

GLUCOSE

INN name

dextrose

Ph. Eur. name

dextrosum / glucosum

Description

Glucose

Record provenance

Inventory reference: 34012
Imported identity: GLUCOSE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for GLUCOSE

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Key data

CAS

50-99-7

200-075-1

Restriction

—

Function

HUMECTANT: Retaining and/or preserving the moisture in a product during use.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#11019 · GLUCOSE

Ingredients with overlapping formulation functions

GLOCHIDION CHODOENSE LEAF EXTRACTHAIR CONDITIONING; HUMECTANT; SKIN PROTECTING; SKIN CONDITIONING - HUMECTANT

GLUCAMINEHAIR CONDITIONING, HUMECTANT

GLUCONACETOBACTER XYLINUS FERMENT FILTRATE EXTRACTHUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

GLUCONOBACTER FERMENT FILTRATEHUMECTANT, SKIN PROTECTING

GLUCOSE GLUTAMATEANTISTATIC, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING

GLUCOSE PENTAISOVALERATEHUMECTANT

GLUCOSYL CERAMIDE NPHAIR CONDITIONING, HUMECTANT

GLUCOSYL HESPERIDINHUMECTANT, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How GLUCOSE appears in the CosIng inventory

The CosIng inventory lists GLUCOSE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

GLUCOSE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

GLUCOSE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, GLUCOSE carries the following function designation(s):

HUMECTANT

CAS 50-99-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for GLUCOSE

This page reproduces the CosIng inventory entry for GLUCOSE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research GLUCOSE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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