Is ERYTHRITOL safe to use in EU cosmetics?

ERYTHRITOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

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Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3379225/09/2015

ERYTHRITOL

Butane-1,2,3,4-tetrol

ERYTHRITOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 149-32-6

CAS 149-32-6PubChem CID 222285

Erythritol

Erythritol is the meso-diastereomer of butane-1,2,3,4-tetrol. It has a role as an antioxidant, a plant metabolite and a human metabolite. — ChEBI

IUPAC name: (2S,3R)-butane-1,2,3,4-tetrol

Molecular formula: C4H10O4
Molecular weight: 122.12 g/mol
Exact mass: 122.05790880 Da
XLogP3: -2.3
Topological polar surface area: 80.9 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 2

Also known as

meso-ErythritolPhycitolErythritMesoerythritolPhyciteL-Erythritol(2R,3S)-butane-1,2,3,4-tetrolAntierythrite

16 more reported names

Erythroglucin1,2,3,4-Butanetetrol, (2R,3S)-rel-Payciteerythro-tetritolTetrahydroxybutaneC*Eridex1,2,3,4-Butanetetrol, (R*,S*)-NIK 242CHEBI:17113RA96B954X6NSC-8099INS NO.968FEMA NO. 4819INS-968F 8015E-968

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External database identifiers

ChEBI:CHEBI:17113
ChEMBL:CHEMBL349605
EPA DTXSID:DTXSID6043919
PubMed:29968805
PubMed:22908895
PubMed:22865539
PubMed:22786800
PubMed:22743789
PubMed:22726439
PubMed:22683210
PubMed:22648525
PubMed:22609752
PubMed:22590580
PubMed:22574125
PubMed:22570720

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 7541-59-5

CAS 7541-59-5PubChem CID 8998

Butane-1,2,3,4-Tetrol

Butane-1,2,3,4-tetrol is a tetritol that is butane substituted by hydroxy groups at positions 1, 2, 3 and 4. — ChEBI

IUPAC name: butane-1,2,3,4-tetrol

Molecular formula: C4H10O4
Molecular weight: 122.12 g/mol
Exact mass: 122.05790880 Da
XLogP3: -2.3
Topological polar surface area: 80.9 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

CHEBI:48299RefChem:122006GlyTouCan:G86724BO231-418-3Tetritol6968-16-71,2,3,4-Butanetetrolbutane-1,2,3,4-tetraol

16 more reported names

1,2,3,4-TetrahydroxybutaneErythritol, meso-DL-1,2,3,4-Butanetetrol2(R),3(S)-1,2,3,4-Butanetetrol1,2,3,4-butanetetraol1,2,3,4-Butanetetrol, [S-(R*,R*)]-1,2,3,4-Butanetetrol, (theta,S)-1,2,3,4-Butanetetrol, (R*,R*)-(A+/-)-Lichen sugarNSC 8099(2R,3R)-1,2,3,4-Butanetetrol7493-90-5EINECS 231-418-3HMS3652N15HMS5082J14NSC-20660

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External database identifiers

ChEBI:CHEBI:48299
ChEMBL:CHEMBL402812
EPA DTXSID:DTXSID70859289
PubMed:22693659
PubMed:22472172
PubMed:22243738
PubMed:20716335
PubMed:20594333
PubMed:20465851
PubMed:20339492
PubMed:19835590
PubMed:19368732
PubMed:18754757
PubMed:18534038
PubMed:18200413

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ERYTHRITOL

INCI name

ERYTHRITOL

Description

Butane-1,2,3,4-tetrol

Record provenance

Inventory reference: 33792
Imported identity: ERYTHRITOL
Source update: 25/09/2015

European Commission CosIng source notes

Annex records for ERYTHRITOL

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Key data

CAS

7541-59-5; 149-32-6

231-418-3; 205-737-3

Restriction

—

Function

HUMECTANT: Retaining and/or preserving the moisture in a product during use.
MOISTURISING: Increasing the water content of the skin and keeping it soft and smooth.
SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#9966 · ERYTHRITOL

Ingredients with overlapping formulation functions

ECHINACEA PURPUREA EXTRACTMOISTURISING, SKIN CONDITIONING, TONIC

ECHINACEA PURPUREA ROOT EXTRACTMOISTURISING, SKIN CONDITIONING, TONIC

ECHINACINMOISTURISING

EMBRYO EXTRACTMOISTURISING, SKIN CONDITIONING

GALLUS EXTRACTMOISTURISING, SKIN CONDITIONING

GLYCINE SOJA FLOURHAIR CONDITIONING, MOISTURISING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

GLYCYRRHIZA GLABRA RHIZOME/ROOTMOISTURISING, SKIN CONDITIONING - EMOLLIENT, SMOOTHING, SOOTHING

HELIANTHUS ANNUUS PETAL EXTRACTCLEANSING, FRAGRANCE, HAIR CONDITIONING, HAIR WAVING OR STRAIGHTENING, MOISTURISING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ERYTHRITOL appears in the CosIng inventory

The CosIng inventory lists ERYTHRITOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ERYTHRITOL is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ERYTHRITOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ERYTHRITOL carries the following function designation(s):

CAS 7541-59-5; 149-32-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for ERYTHRITOL

This page reproduces the CosIng inventory entry for ERYTHRITOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ERYTHRITOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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