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InventoryRef 3375715/10/2010

EICOSAPENTAENOIC ACID

5,8,11,14,17-Eicosapentaenoic acid

EICOSAPENTAENOIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 10417-94-4
CAS 10417-94-4PubChem CID 446284

Icosapent

All-cis-5,8,11,14,17-icosapentaenoic acid is an icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17. It has a role as a micronutrient, an antidepressant, an antineoplastic agent, an anticholesteremic drug, a nutraceutical, a mouse metabolite, a fungal metabolite and a Daphnia galeata metabolite. It is an omega-3 fatty acid and an icosapentaenoic acid. It is a conjugate acid of an all-cis-5,8,11,14,17-icosapentaenoate. — ChEBI

IUPAC name
(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid
Molecular formula
C20H30O2
Molecular weight
302.5 g/mol
Exact mass
302.224580195 Da
XLogP3
5.6
Topological polar surface area
37.3 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

EPAIcosapentoIcosapentumMiraxionEye QEye-QRopufa 70Incromega e 7010sr
16 more reported names
CCRIS 3279AAN7QOV9EAUNII-AAN7QOV9EAIcosapento [INN-Spanish]EPA 45GEPA [drug]C20:5 (n-3)(5Z,8Z,11Z,14Z,17Z)-EicosapentaenoateIcosapentum [INN-Latin]CHEBI:28364C20:5n-3,6,9,12,15EPA (drug)Icosapentum (INN-Latin)Icosapento (INN-Spanish)RELIVENEPA-FFA
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:28364

all-cis-5,8,11,14,17-icosapentaenoic acid

An icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17.

Formula
C20H30O2
Average mass
302.458 g/mol
Monoisotopic mass
302.22458 Da
Formal charge
0
  • icosapentaenoic acid — is a (CHEBI:36006)
  • ω−3 fatty acid — is a (CHEBI:25681)
  • antiviral agent — has role (CHEBI:22587)
  • renoprotective agent — has role (CHEBI:231911)
  • immunosuppressive agent — has role (CHEBI:35705)
  • anti-obesity agent — has role (CHEBI:74518)
  • micronutrient — has role (CHEBI:27027)
  • nutraceutical — has role (CHEBI:50733)
  • Daphnia galeata metabolite — has role (CHEBI:83038)
  • anticholesteremic drug — has role (CHEBI:35821)
  • mouse metabolite — has role (CHEBI:75771)
  • antineoplastic agent — has role (CHEBI:35610)
  • antidepressant — has role (CHEBI:35469)
  • fungal metabolite — has role (CHEBI:76946)
  • geroprotector — has role (CHEBI:176497)
  • antirheumatic drug — has role (CHEBI:35842)
  • anti-asthmatic agent — has role (CHEBI:65023)
  • antipsychotic agent — has role (CHEBI:35476)
  • antiviral agent — has role (CHEBI:22587)
  • renoprotective agent — has role (CHEBI:231911)
  • immunosuppressive agent — has role (CHEBI:35705)
  • anti-obesity agent — has role (CHEBI:74518)
  • micronutrient — has role (CHEBI:27027)
  • nutraceutical — has role (CHEBI:50733)
  • Daphnia galeata metabolite — has role (CHEBI:83038)
  • anticholesteremic drug — has role (CHEBI:35821)
  • mouse metabolite — has role (CHEBI:75771)
  • antineoplastic agent — has role (CHEBI:35610)
  • antidepressant — has role (CHEBI:35469)
  • fungal metabolite — has role (CHEBI:76946)
  • geroprotector — has role (CHEBI:176497)
  • antirheumatic drug — has role (CHEBI:35842)
  • anti-asthmatic agent — has role (CHEBI:65023)
  • antipsychotic agent — has role (CHEBI:35476)
  • cardiovascular drug — has role (CHEBI:35554)
  • anticonvulsant — has role (CHEBI:35623)
  • anti-inflammatory agent — has role (CHEBI:67079)
  • gastrointestinal drug — has role (CHEBI:55324)
  • icosapentaenoic acid — is a (CHEBI:36006)
  • ω−3 fatty acid — is a (CHEBI:25681)
  • all-cis-5,8,11,14,17-icosapentaenoate — is conjugate acid of (CHEBI:58562)
Additional curated names
(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid5,8,11,14,17-EICOSAPENTAENOIC ACID5,8,11,14,17-Icosapentaenoic acid(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-eicosapentaenoic acid(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acidAll-cis-fatty acid 20:5 omega-3C20:5 (n-3)Eicosapentaenoic acidEicosapentaenoic acid (c20:5 n3)(all-Z)-5,8,11,14,17-eicosapentaenoic acidEPAEPA 45Gall-cis-5,8,11,14,17-eicosapentaenoic acidall-cis-icosa-5,8,11,14,17-pentaenoic acidcis-5,8,11,14,17-eicosapentaenoic acidcis-5,8,11,14,17-EPAcis, cis, cis, cis, cis-eicosa-5,8,11,14,17-pentaenoic acidcis-Delta(5,8,11,14,17)-eicosapentaenoic acidicosapentIcosapentaenoic acidIncromega e 7010srRopufa 70Timnodonic acid
Cross-references from this source

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2018-03-05. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match446284

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P260, P264, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 92 reports by companies from 1 notifications to the ECHA C&L Inventory.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

What the official INCI name states

The official label identifies a biological source material and its stated preparation or plant part.

Identity type from wording
biological_material
Scientific-name candidates to verify against the supplier specification
Eicosapentaenoic acid

This structure is derived only from the official label wording. It does not establish composition, concentration, chemical equivalence, safety or regulatory permission.

Inventory details for EICOSAPENTAENOIC ACID

INCI name

EICOSAPENTAENOIC ACID

INN name

icosapent

Description

5,8,11,14,17-Eicosapentaenoic acid

Record provenance

Inventory reference
33757
Imported identity
EICOSAPENTAENOIC ACID
Source update
15/10/2010
European Commission CosIng source notes
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Key data

CAS
10417-94-4
EC
—
Restriction
—
Function
SKIN CONDITIONING
Maintaining the skin in good condition.
SKIN CONDITIONING - EMOLLIENT
Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#9742 · EICOSAPENTAENOIC ACID

Ingredients with overlapping formulation functions

EDENIA GOMEZPOMPAE FERMENT LYSATE EXTRACTANTIOXIDANT; SKIN CONDITIONING - EMOLLIENT; SKIN CONDITIONING - HUMECTANT; SKIN CONDITIONING - MISC…
EEL SKIN MUCUS EXTRACTSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT
EGG SHELL MEMBRANE POWDERANTICAKING, HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT
EICOSANEFRAGRANCE, PERFUMING, SKIN CONDITIONING - EMOLLIENT, SOLVENT
ELAEAGNUS MOLLIS SEED OILANTIOXIDANT, HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT
ELAEAGNUS UMBELLATA BRANCH EXTRACTSKIN CONDITIONING - EMOLLIENT, SKIN CONDITIONING - HUMECTANT
ELAEIS FRUIT OILSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT
ELAEIS GUINEENSIS BUTTERSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, VISCOSITY CONTROLLING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How EICOSAPENTAENOIC ACID appears in the CosIng inventory

The CosIng inventory lists EICOSAPENTAENOIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

EICOSAPENTAENOIC ACID is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

EICOSAPENTAENOIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, EICOSAPENTAENOIC ACID carries the following function designation(s):

CAS 10417-94-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for EICOSAPENTAENOIC ACID

This page reproduces the CosIng inventory entry for EICOSAPENTAENOIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research EICOSAPENTAENOIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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