What does the restriction note for DIRECT RED 80 mean?

The restriction field for DIRECT RED 80 reads: II/1270. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 2610-10-8?

CAS 2610-10-8 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains DIRECT RED 80?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3356715/10/2010

DIRECT RED 80

Hexasodium 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[[2-sulphonato-4-[(4-sulphonatophenyl)azo]phenyl]azo]naphthalene-2-sulphonate] (CI 35780)

DIRECT RED 80 is linked to 1 EU annex record on this page. Inventory note: II/1270.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Evidence linked Prohibited Open this evidence	1	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Prohibited Open this evidence	1	English
ASEAN	Evidence linked Prohibited Open this evidence	1	English and national languages
China	Evidence linked Prohibited Open this evidence	1	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Evidence linked Prohibited Open this evidence	1	Portuguese with INCI crosswalks
India	Evidence linked Prohibited Open this evidence	1	English and Hindi
Saudi Arabia	Evidence linked Prohibited Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 2610-10-8

CAS 2610-10-8PubChem CID 75783

Sirius Red F3B

Sirius red F3B is an organic sodium salt resulting from the formal condensation of Sirius red F3B (acid form) with six equivalents of sodium hydroxide. A polyazo dye used principally in staining methods for collagen and amyloid. It has a role as a fluorochrome and a histological dye. It contains a Sirius red F3B(6-). — ChEBI

IUPAC name: hexasodium;4-hydroxy-7-[[5-hydroxy-7-sulfonato-6-[[2-sulfonato-4-[(4-sulfonatophenyl)diazenyl]phenyl]diazenyl]naphthalen-2-yl]carbamoylamino]-3-[[2-sulfonato-4-[(4-sulfonatophenyl)diazenyl]phenyl]diazenyl]naphthalene-2-sulfonate

Molecular formula: C45H26N10Na6O21S6
Molecular weight: 1373.1 g/mol
Exact mass: 1371.8984406 Da
Topological polar surface area: 574.0 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 29
Covalent units: 7
Defined stereocentres: 0

Also known as

CHEBI:88279RefChem:1098571Direct Red 80C.I. Direct Red 80Sirius Red F 3BSirius Red F 3BASirius RedDiazol Light Red 3B

16 more reported names

Durazol Brillant Red BSC.I. Direct Red 80, hexasodium saltCI 357801294D5G72NHexasodium 7,7'-(carbonyldiimino)bis(4-hydroxy-3-((2-sulphonato-4-((4-sulphonatophenyl)azo)phenyl)azo)naphthalene-2-sulphonate)2-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis(4-hydroxy-3-((2-sulfo-4-((4-sulfophenyl)azo)phenyl)azo)-, hexasodium salt7,7'-(Carbonyldiimino)bis[4-hydroxy-3-[[2-sulfo-4-[(4-sulfophenyl)azo]phenyl]azo]-2-naphthalenesulfonic acid hexasodium saltPicrosirius RedFinisol Red BAFenaluz Red 7B2-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis(4-hydroxy-3-(2-(2-sulfo-4-(2-(4-sulfophenyl)diazenyl)phenyl)diazenyl)-, sodium salt (1:6)HexaNa 7,7'-(carbonyldiimino)bis4-OH-3-2-sulphonato-4-(4-sulphonatophenyl)azophenylazonaphthalene-2-sulphonateDicorel Red L 3ASolophenyl Red 3BLFastusol Red L 8BPyrazoline Red BLWN

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:88279
EPA DTXSID:DTXSID8044628

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for DIRECT RED 80

INCI name

DIRECT RED 80

Description

Hexasodium 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[[2-sulphonato-4-[(4-sulphonatophenyl)azo]phenyl]azo]naphthalene-2-sulphonate] (CI 35780)

Record provenance

Inventory reference: 33567
Imported identity: DIRECT RED 80
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for DIRECT RED 80

Annex II Restriction reference

Entry 1270

2-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis(4-hydroxy-3-[[2-sulfo-4-[(4-sulfophenyl)azo]p…

CAS: 2610-10-8 / 25188-41-4

EC: 220-027-3

Key data

CAS

2610-10-8

220-027-3

Restriction

II/1270

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#9260 · DIRECT RED 80

Ingredients with overlapping formulation functions

DIMETHYLPIPERAZINIUM AMINOPYRAZOLOPYRIDINE HCLHAIR DYEING

DIRECT BLACK 51HAIR DYEING

DIRECT BLUE 86HAIR DYEING

DIRECT RED 23HAIR DYEING

DIRECT RED 81HAIR DYEING

DIRECT VIOLET 48HAIR DYEING

DIRECT YELLOW 12HAIR DYEING

DISPERSE BLACK 9HAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How DIRECT RED 80 appears in the CosIng inventory

The CosIng inventory lists DIRECT RED 80 as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

DIRECT RED 80 is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

DIRECT RED 80 appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for DIRECT RED 80 reads: "II/1270". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, DIRECT RED 80 carries the following function designation(s):

HAIR DYEING

CAS 2610-10-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for DIRECT RED 80

This page combines the CosIng inventory entry for DIRECT RED 80 with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research DIRECT RED 80 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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