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CAS 56-12-2 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 3182815/10/2010

AMINOBUTYRIC ACID

4-Aminobutyric acid

AMINOBUTYRIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 56-12-2

CAS 56-12-2PubChem CID 119

Gamma-Aminobutyric Acid

Gamma-aminobutyric acid is a gamma-amino acid that is butanoic acid with the amino substituent located at C-4. It has a role as a neurotransmitter, a signalling molecule, a Saccharomyces cerevisiae metabolite and a human metabolite. It is a monocarboxylic acid and a gamma-amino acid. It is functionally related to a butyric acid. It is a conjugate acid of a gamma-aminobutyrate. It is a tautomer of a gamma-aminobutyric acid zwitterion. — ChEBI

IUPAC name: 4-aminobutanoic acid

Molecular formula: C4H9NO2
Molecular weight: 103.12 g/mol
Exact mass: 103.063328530 Da
XLogP3: -3.2
Topological polar surface area: 63.3 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

GABAPiperidic acidPiperidinic acidAminalonGaballonMielomadeGamarexGammalon

16 more reported names

GammarGammasolbutanoic acid, 4-amino-GammaloneButyric acid, 4-amino-gamma-Aminobutanoic acidImmu-Ggamma-amino-n-butyric acidGammageeGamulin4-aminobutyrategamma-Aminobuttersaeureomega-Aminobutyric acid4-aminobutanoateAminaloneFactor I

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:16865
ChEMBL:CHEMBL96
EPA DTXSID:DTXSID6035106
PubMed:29968805
PubMed:23112257
PubMed:23105881
PubMed:23076187
PubMed:23050395
PubMed:23049952
PubMed:23038008
PubMed:23036505
PubMed:23028831
PubMed:23019949
PubMed:23002661
PubMed:23000774

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for AMINOBUTYRIC ACID

INCI name

AMINOBUTYRIC ACID

Description

4-Aminobutyric acid

Record provenance

Inventory reference: 31828
Imported identity: AMINOBUTYRIC ACID
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for AMINOBUTYRIC ACID

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Key data

CAS

56-12-2

200-258-6

Restriction

—

Function

HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#1685 · AMINOBUTYRIC ACID

Ingredients with overlapping formulation functions

AMARANTHUS HYPOCHONDRIACUS LEAF EXTRACTHAIR CONDITIONING, SKIN CONDITIONING

AMBER EXTRACTHAIR CONDITIONING, SKIN CONDITIONING

AMIDINOCYSTEINYL HYDROLYZED KERATINASTRINGENT, FILM FORMING, HAIR CONDITIONING, HAIR WAVING OR STRAIGHTENING

AMINO BISPROPYL DIMETHICONEHAIR CONDITIONING, SURFACTANT - EMULSIFYING

AMINOETHYL DISULFIDE KERATINHAIR CONDITIONING

AMINOETHYLAMINOPROPYL PEG-6 DIMETHICONEHAIR CONDITIONING

AMINOLEVULINIC ACID HCLANTIMICROBIAL, HAIR CONDITIONING, SKIN CONDITIONING

AMINOLEVULINOYL SH-PENTAPEPTIDE-19ANTIOXIDANT, HAIR CONDITIONING, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How AMINOBUTYRIC ACID appears in the CosIng inventory

The CosIng inventory lists AMINOBUTYRIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

AMINOBUTYRIC ACID is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

AMINOBUTYRIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, AMINOBUTYRIC ACID carries the following function designation(s):

HAIR CONDITIONING

CAS 56-12-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for AMINOBUTYRIC ACID

This page reproduces the CosIng inventory entry for AMINOBUTYRIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research AMINOBUTYRIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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