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InventoryRef 3171915/10/2010

BUTYL THIOGLYCOLATE

Butyl mercaptoacetate

BUTYL THIOGLYCOLATE is linked to 1 EU annex record on this page. Inventory note: III/2b.

Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Restricted entry found
Open this evidence
1English and EU languages
Great BritainSource mapped
Official source mapped; ingredient rule not imported
0English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandSource mapped
Official source mapped; ingredient rule not imported
0English
ASEANSource mapped
Official source mapped; ingredient rule not imported
0English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaSource mapped
Official source mapped; ingredient rule not imported
0English and Hindi
Saudi ArabiaSource mapped
Official source mapped; ingredient rule not imported
0Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 10047-28-6
CAS 10047-28-6PubChem CID 82321

Butyl Thioglycolate

Based on the available data, the CIR Expert Panel concluded that ... Butyl Thioglycolate is safe for use in hair straighteners, permanent waves, tonics, dressings, and so forth, wave sets, other non-coloring hair products, and hair dyes and colors, as described in this safety assessment, at concentrations up to 15.2% (as Thioglycolic Acid). Hairdressers should avoid skin contact and minimize consumer skin exposure. Cosmetic Ingredient Review (CIR)

IUPAC name
butyl 2-sulfanylacetate
Molecular formula
C6H12O2S
Molecular weight
148.23 g/mol
Exact mass
148.05580079 Da
XLogP3
1.7
Topological polar surface area
27.3 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

Butyl mercaptoacetateButyl 2-mercaptoacetateAcetic acid, 2-mercapto-, butyl esterAcetic acid, mercapto-, butyl ester96L21ZJ8JCEINECS 233-156-5NSC 65453NSC-65453
16 more reported names
AI3-63085THIOGLYCOLIC ACID N-BUTYL ESTERefChem:571789BUTYL THIOGLYCOLATE [INCI]233-156-5THIOGLYCOLIC ACID N-BUTYL ESTERTHIOGLYCOLICACIDN-BUTYLESTERButyl thioglicolaten-Butyl thioglycolateUNII-96L21ZJ8JCMercaptoacetic Acid Butyl EsterButyl sulfanylacetateButyl sulfanylacetate #Thioglycolic Acid Butyl EsterSKGVGRLWZVRZDC-UHFFFAOYSA-DB-254125
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match82321

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H301 (97.6%): Toxic if swallowed [Danger Acute toxicity, oral]; H311 (97.6%): Toxic in contact with skin [Danger Acute toxicity, dermal]; H331 (97.6%): Toxic if inhaled [Danger Acute toxicity, inhalation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P262, P264, P270, P271, P280, P301+P316, P302+P352, P304+P340, P316, P321, P330, P361+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 41 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Cosmetic Ingredient Review Conclusion: Based on the available data, the CIR Expert Panel concluded that ... Butyl Thioglycolate is safe for use in hair straighteners, permanent waves, tonics, dressings, and so forth, wave sets, other non-coloring hair products, and hair dyes and colors, as described in this safety assessment, at concentrations up to 15.2% (as Thioglycolic Acid). Hairdressers should avoid skin contact and minimize consumer skin exposure. Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBINo exact record2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for BUTYL THIOGLYCOLATE

INCI name

BUTYL THIOGLYCOLATE

Description

Butyl mercaptoacetate

Record provenance

Inventory reference
31719
Imported identity
BUTYL THIOGLYCOLATE
Source update
15/10/2010
European Commission CosIng source notes

Key data

Restriction
III/2b
Function
HAIR WAVING OR STRAIGHTENING
Modifying the chemical structure of the hair, allowing it to be set in the style required (permanent waves or hair straightening).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How BUTYL THIOGLYCOLATE appears in the CosIng inventory

The CosIng inventory lists BUTYL THIOGLYCOLATE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

BUTYL THIOGLYCOLATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

BUTYL THIOGLYCOLATE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for BUTYL THIOGLYCOLATE reads: "III/2b". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, BUTYL THIOGLYCOLATE carries the following function designation(s):

CAS 10047-28-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for BUTYL THIOGLYCOLATE

This page combines the CosIng inventory entry for BUTYL THIOGLYCOLATE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research BUTYL THIOGLYCOLATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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