What does the restriction note for ACID ORANGE 3 mean?

The restriction field for ACID ORANGE 3 reads: II/1280. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 6373-74-6?

CAS 6373-74-6 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains ACID ORANGE 3?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3161815/10/2010

ACID ORANGE 3

Sodium 2-anilino-5-(2,4-dinitroanilino)benzenesulphonate (CI 10385)

ACID ORANGE 3 is linked to 1 EU annex record on this page. Inventory note: II/1280.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Evidence linked Prohibited Open this evidence	1	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Prohibited Open this evidence	1	English
ASEAN	Evidence linked Prohibited Open this evidence	1	English and national languages
China	Evidence linked Prohibited Open this evidence	1	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Evidence linked Prohibited Open this evidence	1	Portuguese with INCI crosswalks
India	Evidence linked Prohibited Open this evidence	1	English and Hindi
Saudi Arabia	Evidence linked Prohibited Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 6373-74-6

CAS 6373-74-6PubChem CID 5284435

C.I. Acid Orange 3

CI Acid Orange 3 is an organic molecular entity. — ChEBI

IUPAC name: sodium 2-anilino-5-(2,4-dinitroanilino)benzenesulfonate

Molecular formula: C18H13N4NaO7S
Molecular weight: 452.4 g/mol
Exact mass: 452.04026422 Da
Topological polar surface area: 181.0 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 9
Covalent units: 2
Defined stereocentres: 0

Also known as

Acid Orange 3Amido yellow EAAmido Yellow EAcid Yellow EAiredale Yellow ECI 10385Sodium 2-anilino-5-(2,4-dinitroanilino)benzenesulphonateP0XV7XM57J

16 more reported names

sodium;2-anilino-5-(2,4-dinitroanilino)benzenesulfonateAcid Orange 3, Technical GradeBenzenesulfonic acid, 5-((2,4-dinitrophenyl)amino)-2-(phenylamino)-, monosodium saltDerma Yellow PFenalan Yellow EErio Yellow AEN5-((2,4-Dinitrophenyl)amino)-2-(phenylamino)benzenesulfonic acid, monosodium saltSolanile Yellow ESuperian Yellow RLissamine Yellow AEMultacid Yellow 3RNylocrom Yellow 3RMulticuer Brown MPHSellacid Yellow AENPolan Yellow E-3RFast Light Yellow E

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:82425
ChEMBL:CHEMBL3181851
EPA DTXSID:DTXSID1021081

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ACID ORANGE 3

INCI name

ACID ORANGE 3

Description

Sodium 2-anilino-5-(2,4-dinitroanilino)benzenesulphonate (CI 10385)

Record provenance

Inventory reference: 31618
Imported identity: ACID ORANGE 3
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for ACID ORANGE 3

Annex II Restriction reference

Entry 1280

Benzenesulfonic acid, 5-[(2,4-dinitrophenyl]amino]-2-(phenylamino)-, and its salts, when used as a …

CAS: 6373-74-6 / 15347-52-1

EC: 228-921-5 / 239-377-3

Key data

CAS

6373-74-6

228-921-5

Restriction

II/1280

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#857 · ACID ORANGE 3

Ingredients with overlapping formulation functions

ACID BLUE 9 AMMONIUM SALTHAIR DYEING

ACID BROWN 13HAIR DYEING

ACID GREEN 1HAIR DYEING

ACID ORANGE 24HAIR DYEING

ACID ORANGE 6HAIR DYEING

ACID ORANGE 7HAIR DYEING

ACID RED 18HAIR DYEING

ACID RED 18 ALUMINUM LAKEHAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ACID ORANGE 3 appears in the CosIng inventory

The CosIng inventory lists ACID ORANGE 3 as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ACID ORANGE 3 is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ACID ORANGE 3 appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for ACID ORANGE 3 reads: "II/1280". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, ACID ORANGE 3 carries the following function designation(s):

HAIR DYEING

CAS 6373-74-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ACID ORANGE 3

This page combines the CosIng inventory entry for ACID ORANGE 3 with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research ACID ORANGE 3 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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