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InventoryRef 3158315/10/2010

ACETYL METHIONINE

N-acetylmethionine

ACETYL METHIONINE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 1115-47-5
CAS 1115-47-5PubChem CID 6180

N-Acetyl-DL-methionine

N-acetylmethionine is a methionine derivative that is methionine in which one of the amine hydrogens is substituted by an acetyl group. It is a methionine derivative, a monocarboxylic acid, a N-acyl-amino acid and a methyl sulfide. It is a conjugate acid of a N-acetylmethioninate. — ChEBI

IUPAC name
2-acetamido-4-methylsulfanylbutanoic acid
Molecular formula
C7H13NO3S
Molecular weight
191.25 g/mol
Exact mass
191.06161445 Da
XLogP3
0.1
Topological polar surface area
91.7 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

METHIONINE, N-ACETYL-RefChem:828872Ac-DL-Met-OHAcetyl-DL-methionineDL-Methionine, N-acetyl-DL-N-Acetylmethionine2-Acetamido-4-(methylthio)butanoic acidMethionine, N-acetyl-, DL-
16 more reported names
N-Acetylmethionine, DL-Methionine EP Impurity CN-ACETYL-METHIONINENSC 7633dl-Acetylmethionine2-acetamido-4-methylsulfanyl-butanoic acidN-acetyl-D,L-methionine2-acetamido-4-(methylsulfanyl)butanoic acidNSC-7633AC-15650CS-0031301N-ACETYL-D,L-METHIONINE [USP IMPURITY]N-Acetyl(methyl)homocysteine4-04-00-03205 (Beilstein Handbook Reference)EINECS 214-224-3N-Acetyl(methyl)homocysteine #
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match6180

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 66.7% (4 of 6) of all reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H318 (33.3%): Causes serious eye damage [Danger Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P264+P265, P280, P305+P354+P338, and P317 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 6 reports by companies from 2 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 4 of 6 reports by companies.; There is 1 notification provided by 2 of 6 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 65-82-7
CAS 65-82-7PubChem CID 448580

N-acetyl-L-methionine

N-acetyl-L-methionine is an L-methionine derivative that is L-methionine in which one of the amine hydrogens is substituted by an acetyl group. It has a role as a nutraceutical. It is a N-acetylmethionine, a N-acetyl-L-amino acid and a L-methionine derivative. It is a conjugate acid of a N-acetyl-L-methionine(1-). It is an enantiomer of a N-acetyl-D-methionine. — ChEBI

IUPAC name
(2S)-2-acetamido-4-methylsulfanylbutanoic acid
Molecular formula
C7H13NO3S
Molecular weight
191.25 g/mol
Exact mass
191.06161445 Da
XLogP3
0.1
Topological polar surface area
91.7 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
1

Also known as

N-AcetylmethionineAcetyl-L-methionineMethionamineThiomedonAcetylmethionineL-(N-Acetyl)methionineL-Methionine, N-acetyl-Methionin
16 more reported names
AcMetMethionine, N-acetyl-, L-N-Ac-MetNalpha-acetyl-L-methionine(2S)-2-acetamido-4-(methylsulfanyl)butanoic acidFOLLICUSAN9J12WX5B6ACHEBI:21557NSC-118514N-Ac-L-methionineRefChem:162765200-617-7Ac-Met-OHacetyl methionineAcetylmethionin(S)-2-acetamido-4-(methylthio)butanoic acid
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ACETYL METHIONINE

INCI name

ACETYL METHIONINE

Description

N-acetylmethionine

Record provenance

Inventory reference
31583
Imported identity
ACETYL METHIONINE
Source update
15/10/2010
European Commission CosIng source notes
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Key data

CAS
1115-47-5 / 65-82-7
EC
214-224-3 / 200-617-7
Restriction
—
Function
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#673 · ACETYL METHIONINE

Ingredients with overlapping formulation functions

ACETYL HYDROGENATED CITRONELLOL/GERANIOL/NEROL COPOLYMERFILM FORMING, FRAGRANCE, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT
ACETYL HYDROXYPROLINEHAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING
ACETYL LACTOSAMINEANTIMICROBIAL, BLEACHING, SKIN CONDITIONING
ACETYL MANNOSYLERYTHRITOL LIPIDEMULSION STABILISING, HAIR CONDITIONING, SKIN CONDITIONING, SURFACTANT - CLEANSING
ACETYL METHYL HYDROXYPROLINATYL GLYCYRRHETINATESKIN CONDITIONING
ACETYL OCTAPEPTIDE-17 AMIDESKIN CONDITIONING
ACETYL OCTAPEPTIDE-2SKIN CONDITIONING
ACETYL OCTAPEPTIDE-29 AMIDESKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How ACETYL METHIONINE appears in the CosIng inventory

The CosIng inventory lists ACETYL METHIONINE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ACETYL METHIONINE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ACETYL METHIONINE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ACETYL METHIONINE carries the following function designation(s):

CAS 1115-47-5 / 65-82-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ACETYL METHIONINE

This page reproduces the CosIng inventory entry for ACETYL METHIONINE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ACETYL METHIONINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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