What does the restriction note for ACETYL HEXAMETHYL TETRALIN mean?

The restriction field for ACETYL HEXAMETHYL TETRALIN reads: III/182. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

How do I check if my formula contains ACETYL HEXAMETHYL TETRALIN?

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InventoryRef 3158115/10/2010

ACETYL HEXAMETHYL TETRALIN

1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one

ACETYL HEXAMETHYL TETRALIN is linked to 1 EU annex record on this page. Inventory note: III/182.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Restricted entry found Open this evidence	1	English and EU languages
Great Britain	Evidence linked Restricted Open this evidence	1	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Restricted Open this evidence	2	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Evidence linked Restricted Open this evidence	1	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Evidence linked Restricted Open this evidence	1	English and Hindi
Saudi Arabia	Evidence linked Restricted Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 1506-02-1

CAS 1506-02-1CAS 21145-77-7PubChem CID 89440

Tonalide

2-Acetyl-3,5,5,6,8,8-hexamethyl-5,6,7,8- tetrahydronaphthalene is a member of tetralins. — ChEBI

IUPAC name: 1-(3,5,5,6,8,8-hexamethyl-6,7-dihydronaphthalen-2-yl)ethanone

Molecular formula: C18H26O
Molecular weight: 258.4 g/mol
Exact mass: 258.198365449 Da
XLogP3: 5.3
Topological polar surface area: 17.1 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 1
Covalent units: 1
Defined stereocentres: 0

Also known as

TonalidTetralideAHTNTentaromeMusk tonalidAHMT (perfume)360Q8Z01IP2'-Acetonaphthone, 5',6',7',8'-tetrahydro-3',5',5',6',8',8'-hexamethyl-

16 more reported names

RefChem:8986116-Acetyl-1,1,2,4,4,7-hexamethyltetralin1-(3,5,5,6,8,8-hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanonefixolideAcetyl hexamethyl tetralin1-(3,5,5,6,8,8-hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethan-1-oneEthanone, 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl)-C18H26O7-Acetyl-1,1,3,4,4,6-hexamethyltetralinNSC-195506-acetyl-1,1,2,4,4,7-hexamethyltetraline1-(3,5,5,6,8,8-Hexamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)ethanone1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl)-ethanone1-(5,6,7,8-Tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one2-Acetyl-3,5,5,6,8,8-hexamethyl-5,6,7,8- tetrahydronaphthalene1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl)ethanone

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:88666
ChEMBL:CHEMBL3184267
EPA DTXSID:DTXSID7041544
PubMed:40048564
PubMed:34687775
PubMed:34323617
PubMed:33049310
PubMed:28927721
PubMed:25088042
PubMed:24155963
PubMed:23084589
PubMed:22709983
PubMed:22684881
PubMed:22649449
PubMed:22489002

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ACETYL HEXAMETHYL TETRALIN

INCI name

ACETYL HEXAMETHYL TETRALIN

Description

1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one

Record provenance

Inventory reference: 31581
Imported identity: ACETYL HEXAMETHYL TETRALIN
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for ACETYL HEXAMETHYL TETRALIN

Annex III Restriction reference

Entry 182

1-(5,6,7,8-Tetrahydro-3,5,5,6,8,8,-hexamethyl-2-naphthyl)ethan-1-one (AHTN)

CAS: 21145-77-7 - 1506-02-1

EC: 244-240-6 - 216-133-4

Key data

CAS

1506-02-1 / 21145-77-7

216-133-4 / 244-240-6

Restriction

III/182

Function

FRAGRANCE: Imparting an odour or taste. Creating a perceivable pleasant smell and/or masking a bad smell.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#639 · ACETYL HEXAMETHYL TETRALIN

Ingredients with overlapping formulation functions

ACETIC ACIDBUFFERING, FRAGRANCE

ACETONEDENATURANT, FRAGRANCE, SOLVENT

ACETOPHENONEFRAGRANCE

ACETYL HEXAMETHYL INDANFRAGRANCE, PERFUMING

ACETYL HYDROGENATED CITRONELLOL/GERANIOL/NEROL COPOLYMERFILM FORMING, FRAGRANCE, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

ACETYL TRIBUTYL CITRATEFRAGRANCE, PERFUMING, PLASTICISER

ACETYL TRIETHYL CITRATEFILM FORMING, FRAGRANCE, PERFUMING, PLASTICISER

ACETYLBENZOFURANFRAGRANCE, PERFUMING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ACETYL HEXAMETHYL TETRALIN appears in the CosIng inventory

The CosIng inventory lists ACETYL HEXAMETHYL TETRALIN as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ACETYL HEXAMETHYL TETRALIN is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ACETYL HEXAMETHYL TETRALIN appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for ACETYL HEXAMETHYL TETRALIN reads: "III/182". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, ACETYL HEXAMETHYL TETRALIN carries the following function designation(s):

FRAGRANCE

CAS 1506-02-1 / 21145-77-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ACETYL HEXAMETHYL TETRALIN

This page combines the CosIng inventory entry for ACETYL HEXAMETHYL TETRALIN with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research ACETYL HEXAMETHYL TETRALIN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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