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CAS 3687-18-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 3151315/10/2010

3-AMINOPROPANE SULFONIC ACID

3-aminopropane-1-sulphonic acid

3-AMINOPROPANE SULFONIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 3687-18-1

CAS 3687-18-1PubChem CID 1646

Tramiprosate

3-aminopropanesulfonic acid is an amino sulfonic acid that is the 3-amino derivative of propanesulfonic acid. It has a role as an anticonvulsant, a GABA agonist, a nootropic agent, an anti-inflammatory agent and an algal metabolite. It is a tautomer of a 3-aminopropanesulfonic acid zwitterion. — ChEBI

IUPAC name: 3-aminopropane-1-sulfonic acid

Molecular formula: C3H9NO3S
Molecular weight: 139.18 g/mol
Exact mass: 139.03031432 Da
XLogP3: -3.8
Topological polar surface area: 88.8 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

Homotaurine1-Propanesulfonic acid, 3-amino-3-aminopropanesulphonic acidAlzhemed3APS3-aminopropanesulfonic acid3-Aminopropane sulfonic acid3-aminopropylsulfonic acid

16 more reported names

3-APSNC-531Tramiprosato5K8EAX0G53NSC-77071tramiprosatumLU-02659NC531 cpdRefChem:898661222-977-43-Amino-1-propanesulfonic acidCerebril3-Aminopropanesulfonate3-Aminopropiosulfonic AcidTramiprosate [USAN]EINECS 222-977-4

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:1457
ChEMBL:CHEMBL149082
EPA DTXSID:DTXSID80190352
PubMed:22932902
PubMed:22877150
PubMed:22785403
PubMed:22654847
PubMed:22654725
PubMed:22529838
PubMed:22506132
PubMed:22403554
PubMed:22346357
PubMed:22291741
PubMed:22199538
PubMed:22110489

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for 3-AMINOPROPANE SULFONIC ACID

INCI name

3-AMINOPROPANE SULFONIC ACID

Description

3-aminopropane-1-sulphonic acid

Record provenance

Inventory reference: 31513
Imported identity: 3-AMINOPROPANE SULFONIC ACID
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for 3-AMINOPROPANE SULFONIC ACID

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Key data

CAS

3687-18-1

222-977-4

Restriction

—

Function

SURFACTANT - CLEANSING: Wetting body surfaces, emulsifying or solubilizing oils, and suspending soil (generally, such ingredients contribute to the foaming and lathering properties of cleansing products).
SURFACTANT - HYDROTROPE: Enhancing the water solubility of another surfactant.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#269 · 3-AMINOPROPANE SULFONIC ACID

Ingredients with overlapping formulation functions

ALMONDAMIDOPROPYLAMINE OXIDECLEANSING, FOAMING, SURFACTANT - HYDROTROPE

AMMONIUM CUMENESULFONATESURFACTANT - CLEANSING, SURFACTANT - HYDROTROPE

AMMONIUM XYLENESULFONATESURFACTANT - CLEANSING, SURFACTANT - HYDROTROPE, VISCOSITY CONTROLLING

ARACHIDYL/BEHENYL ALCOHOLSURFACTANT - CLEANSING, SURFACTANT - DISPERSING, SURFACTANT - EMULSIFYING, SURFACTANT - FOAM BOOSTI…

ARACHIDYL/BEHENYL BETAINATE ESYLATECLEANSING, SURFACTANT - CLEANSING, SURFACTANT - DISPERSING, SURFACTANT - EMULSIFYING, SURFACTANT - …

ARACHIDYL/BEHENYL BETAINATE MESYLATECLEANSING, SURFACTANT - CLEANSING, SURFACTANT - DISPERSING, SURFACTANT - EMULSIFYING, SURFACTANT - …

BABASSUAMIDOPROPYLAMINE OXIDECLEANSING, FOAMING, HAIR CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - HYDROTROPE

BEHENAMINE OXIDECLEANSING, FOAMING, SURFACTANT - CLEANSING, SURFACTANT - HYDROTROPE

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How 3-AMINOPROPANE SULFONIC ACID appears in the CosIng inventory

The CosIng inventory lists 3-AMINOPROPANE SULFONIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

3-AMINOPROPANE SULFONIC ACID is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

3-AMINOPROPANE SULFONIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, 3-AMINOPROPANE SULFONIC ACID carries the following function designation(s):

CAS 3687-18-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for 3-AMINOPROPANE SULFONIC ACID

This page reproduces the CosIng inventory entry for 3-AMINOPROPANE SULFONIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research 3-AMINOPROPANE SULFONIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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