Lauryldimethylamine
- IUPAC name
- N,N-dimethyldodecan-1-amine
- Molecular formula
- C14H31N
- Molecular weight
- 213.40 g/mol
- Exact mass
- 213.245649993 Da
- XLogP3
- 5.9
- Topological polar surface area
- 3.2 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 1
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:229425
- ChEMBL:CHEMBL109737
- EPA DTXSID:DTXSID1026906
- PubMed:22364564
- PubMed:22147702
- PubMed:22011142
- PubMed:21845225
- PubMed:21674806
- PubMed:21280645
- PubMed:20371068
- PubMed:20351097
- PubMed:20298860
- PubMed:19768228
- PubMed:19615819
- PubMed:18572919
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Color/Form: Liquid Source: Hazardous Substances Data Bank (HSDB)
- Physical Description: N,n-dimethyldodecylamine appears as a clear yellow liquid with a fishlike odor. Insoluble in water and less dense than water. Hence floats on water. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion, inhalation or skin absorption. Used to make other chemicals. Source: CAMEO Chemicals
- Physical Description: Liquid; CBI Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Clear yellow liquid with a fishy odor; [CAMEO] Clear colorless liquid; [MSDSonline] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Vapor Pressure: 0.01 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
- Note: This chemical does not meet GHS hazard criteria for 1.1% (12 of 1116) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302 (98.7%): Harmful if swallowed [Warning Acute toxicity, oral]; H314 (97.5%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H318 (78%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H400 (96.1%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410 (65.2%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P260, P264, P264+P265, P270, P273, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P363, P391, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 1116 reports by companies from 27 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 12 of 1116 reports by companies.; There are 26 notifications provided by 1104 of 1116 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: NITE-CMC
- GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
- Precautionary Statement Codes: P260, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P319, P321, P330, P363, P391, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
- GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] Source: NITE-CMC
- Precautionary Statement Codes: P203, P260, P264, P264+P265, P270, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P318, P321, P330, P363, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
- Signal: Danger Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
- GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
- Cosmetic Ingredient Review Finding(s): Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org Source: Cosmetic Ingredient Review (CIR)
- Environmental Bioconcentration: An estimated BCF of 310 was calculated for N,N-dimethyl-1-dodecanamine(SRC), using an estimated log Kow of 5.4(1,SRC) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is high(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 21,700(SRC), determined from an estimated log Kow of 5.4(2,SRC) and a regression-derived equation(3), indicates that N,N-dimethyl-1-dodecanamine is expected to be immobile in soil(SRC). Volatilization of N,N-dimethyl-1-dodecanamine from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 4.9X10-3 atm-cu m/mole(SRC), using a fragment constant estimation method(4); however, adsorption may attenuate this process(SRC). N,N-Dimethyl-1-dodecanamine is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 0.016 mm Hg(SRC), determined from a fragment constant method(5). N,N-Dimethyl-1-dodecanamine, present at 100 mg/l, achieved 49.4% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/l and the Japanese MITI test(6). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 21,700(SRC), determined from an estimated log Kow of 5.4(2,SRC) and a regression-derived equation(3), indicates that N,N-dimethyl-1-dodecanamine is expected to adsorb to suspended solids and sediment in water(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 4.9X10-3 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4); however, adsorption may attenuate this process(SRC). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 2 hours and 6 days, respectively if adsorption is neglected(SRC). The volatilization half-life from a model pond is about 160 days when adsorption is considered(5). According to a classification scheme(6), an estimated BCF of 310(SRC), from its estimated log Kow(2) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is high(SRC). N,N-Dimethyl-1-dodecanamine, present at 100 mg/l, achieved 49.4% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/l and the Japanese M Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), N,N-dimethyl-1-dodecanamine, which has an estimated vapor pressure of 0.016 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase N,N-dimethyl-1-dodecanamine is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 4 hours(SRC), calculated from its rate constant of 9.3X10-11 cu cm/molecule-sec at 25 °C(3) determined using a structure estimation method(3). Source: Hazardous Substances Data Bank (HSDB)
- Consumer Uses: Surfactant (surface active agent); Soil amendments (fertilizers) Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Antioxidant; Surfactant (surface active agent); Corrosion inhibitor; Not Known or Reasonably Ascertainable; Catalyst; Intermediate Source: EPA Chemical Data Reporting (CDR)
- Cosmetic Ingredient Review Link: CIR ingredient: Dimethyl Lauramine Source: Cosmetic Ingredient Review (CIR)
- Sources/Uses: Used as corrosion inhibitor, acid-stable emulsifier, cationic detergent, and intermediate in chemical synthesis; [HSDB] Commonly found in commercial mixtures with C12-14 alkyldimethylamine (CAS 84649-84-3); Used to make amineoxides, betaines, and quaternary amino compounds with end-uses as disinfectants, detergents, textile chemicals, pharmaceuticals, corrosion inhibitors, etc.; [SIDSUNEP] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: Corrosion inhibitor; acid-stable emulsifier; as cationic detergent Source: Hazardous Substances Data Bank (HSDB)
- Uses: USED TO SYNTHESIZE A MICROBIOCIDE FROM REACTION PRODUCT OF CHLOROMETHYLATED CROSS-LINKED POLYSTYRENE Source: Hazardous Substances Data Bank (HSDB)
- Uses: CHEM INT FOR N,N-DIMETHYL-N-DODECANAMINE OXIDE Source: Hazardous Substances Data Bank (HSDB)
- Uses: CHEM INT FOR BENZYL DIMETHYL DODECYL AMMONIUM CHLORIDE Source: Hazardous Substances Data Bank (HSDB)
- Uses: FILMING AMINE CORROSION INHIBITOR FOR CONDENSING SYSTEMS Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.