Official EU label nameGlossary entry 28748

THIMEROSAL

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 4 of 13 indexed market datasets: 4 country records and 1 EU Annex records. Every result and evidence gap is listed below.

4 markets with evidence
Markets checked
13
Markets with evidence
4
Evidence gaps
9
Resolved identifiers
8

A missing local match is not permission, approval or proof of safety. It means no strong identity match was resolved in that indexed dataset.

Resolved substance identity

CAS:54-64-87439-97-621908-53-262-38-494-43-9102-98-76273-99-0
EC:200-210-4
Ingredient index records:
THIMEROSAL
Cosmetic functions: PRESERVATIVE

Mercurate(1-), ethyl[2-mercaptobenzoato(2-)-O, S]-, sodium

Inventory restriction note: V/16

5 matched or reported names
THIMEROSALthiomersalThiomersalThimerosalMercury and its compounds

Regulatory evidence in all 13 markets

Open each matched record for its scope, concentration, conditions, warnings and official source version.

Swipe or scroll horizontally to see dataset coverage and next actions.

MarketResultRecordsDatasetMeaning / next action
European Union
EU
Conditional positive-list match1Open record 1
Complete annex dataset
Regulation (EC) 1223/2009 consolidated to 1 May 2026
Review every linked record and exact conditions.
Great Britain
GB
Permitted list with conditions1Open record 1
Complete consolidated annex dataset
GB retained Regulation 1223/2009 schedules, effective 15 August 2026
Review every linked record and exact conditions.
Canada
CA
Prohibited2Open record 1Open record 2
Complete Hotlist snapshot
Health Canada Cosmetic Ingredient Hotlist, 13 August 2025
Review every linked record and exact conditions.
New Zealand
NZ
Permitted list with conditions1Open record 1
Complete schedules dataset
Cosmetic Products Group Standard schedules effective 1 January 2026
Review every linked record and exact conditions.
ASEAN
ASEAN
No local match0
Complete regional annex dataset
ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026
Regional annex coverage does not replace member-state implementation dates, notifications or national deviations.
China
CN
No local match0
Complete prohibited catalogues plus official-source workflow
NMPA 2021 banned catalogues plus dynamic IECIC List I/List II system current since 2025
IECIC listing is not blanket approval; absence may require the new cosmetic ingredient route, and restrictions are checked separately.
Japan
JP
No local match0
Complete Standards appendices dataset
MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshot
The Japanese text and subsequent notices are canonical; no local match is not a product-compliance conclusion.
South Korea
KR
No local match0
Complete current appendix dataset
MFDS Notice 2026-19, effective 18 March 2026
Korean source wording is canonical and other positive lists/notices may still apply to the formulation.
United States
US
No local match0
Complete enumerated federal ingredient rules
eCFR Title 21 issue date 27 August 2026
FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety.
Australia
AU
No local match0
Complete cosmetic-relevant Poisons Standard subset plus official workflow
Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026
An AICIS Inventory match is not cosmetic approval; no Inventory match can indicate a new, exempted, reported or confidential introduction.
Brazil
BR
No local match0
Complete prohibited dataset plus current restricted-list workflow
ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026
RDC 1.030/2026 amends rather than replaces the prohibited baseline, and the second restricted-list revision was still under consultation in July 2026.
India
IN
No local match0
Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4
Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022)
The standards are separate controlled publications; absence from a locally indexed excerpt is not permission.
Saudi Arabia
SA
No local match0
Complete official list index
SFDA live prohibited/restricted lists, snapshot 30 August 2026
No list match is not permission; Gulf/SFDA product, claim, notification and technical requirements still apply.
No market rows match this filter.

Matching market records and conditions

Exact Annex II–VI evidence

THIMEROSAL

Product scope: Eye products

Maximum concentration: 0.007% (of Hg) If mixed with other mercurial compounds authorized by this Regulation, the maximum concentration of Hg remains fixed at 0.007%

Warnings: Contains Thiomersal

Chemical identity and properties

PubChem 2D chemical structure for CAS 102-98-7
CAS 102-98-7PubChem CID 16683761

Phenylmercury borate

IUPAC name
boronooxy(phenyl)mercury
Molecular formula
C6H7BHgO3
Molecular weight
338.52 g/mol
Exact mass
340.019468 Da
Topological polar surface area
49.7 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

FamoseptFenoseptSpidoxolSpidoxRyfenPhenylmercuriboratePhenyl mercuric borateNSC-163948
11 more reported names
phenylhydrargyri borasRefChem:173090203-068-1(dihydrogen borato)phenylmercuryZT1TTY3NGJPhenylmercuriboratMercurate(2-), dihydrogendihydrogen borate;phenylmercury(1+)DB-040400Mercurate(2-), [orthoborato(3-)-.kappa.O]phenyl-, dihydrogenMercurate(2-), [orthoborato(3-)-kappaO]phenyl-, hydrogen (1:2)

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match16683761

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 7% (3 of 43) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H300 (93%): Fatal if swallowed [Danger Acute toxicity, oral]; H310 (93%): Fatal in contact with skin [Danger Acute toxicity, dermal]; H330 (93%): Fatal if inhaled [Danger Acute toxicity, inhalation]; H373 (93%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]; H400 (90.7%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410 (90.7%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P260, P262, P264, P270, P271, P273, P280, P284, P301+P316, P302+P352, P304+P340, P316, P319, P320, P321, P330, P361+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 43 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 3 of 43 reports by companies.; There are 3 notifications provided by 40 of 43 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Health Effects: Mercury mainly affects the nervous system. Exposure to high levels of metallic, inorganic, or organic mercury can permanently damage the brain, kidneys, and developing fetus. Effects on brain functioning may result in irritability, shyness, tremors, changes in vision or hearing, and memory problems. Acrodynia, a type of mercury poisoning in children, is characterized by pain and pink discoloration of the hands and feet. Mercury poisoning can also cause Hunter-Russell syndrome and Minamata disease. (L7) Source: Toxin and Toxin Target Database (T3DB)
  • Toxicity Summary: High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through alterations in intracellular thiol status, mercury can promote oxidative stress, lipid peroxidation, mitochondrial dysfunction, and changes in heme metabolism. Mercury is known to bind to microsomal and mitochondrial enzymes, resulting in cell injury and death. For example, mercury is known to inhibit aquaporins, halting water flow across the cell membrane. It also inhibits the protein LCK, which causes decreased T-cell signalling and immune system depression. Mercury is also believed to inhibit neuronal excitability by acting on the postsynaptic neuronal membrane. It also affects the nervous system by inhibiting protein kinase C and alkaline phosphatase, which impairs brain microvascular formation and function, as well as alters the blood-brain barrier. Organic mercury exerts developmental effects by binding to tubulin, preventing microtubule assembly and causing mitotic inhibition. Mercury also produces an autoimmune response, likely by modification of major histocompatibility complex (MHC) class II molecules, self Source: Toxin and Toxin Target Database (T3DB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBINo exact record2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 21908-53-2
CAS 21908-53-2PubChem CID 30856

Mercuric oxide

IUPAC name
oxomercury
Molecular formula
HgO
Molecular weight
216.59 g/mol
Exact mass
217.965558 Da
Topological polar surface area
17.1 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Covalent units
1
Defined stereocentres
0

Also known as

Mercury(II) oxideMercuric oxide, redSantarRed PrecipitateRed mercuric oxideMercury oxide (HgO)Mercuric oxide, yellowSantar M
16 more reported names
Yellow precipitateMercuric oxide redNatural montroyditeMercury(2+) oxideRed oxide of mercuryGelbes quecksilberoxydHydrargyrum oxid flavYellow mercuric oxideMercuric oxide (red)Oxide mercurique jauneMercuric oxide (HgO)Caswell No. 544AYellow oxide of mercuryOxido amarillo de mercurioOxyde de mercureEPA Pesticide Chemical Code 052102
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 54-64-8
CAS 54-64-8PubChem CID 16684434

Thimerosal

Thimerosal is an alkylmercury compound (approximately 49% mercury by weight) used as an antiseptic and antifungal agent. It has a role as an antiseptic drug, a disinfectant, an antifungal drug and a drug allergen. It contains an ethylmercurithiosalicylate. ChEBI

IUPAC name
sodium (2-carboxylatophenyl)sulfanyl-ethylmercury
Molecular formula
C9H9HgNaO2S
Molecular weight
404.82 g/mol
Exact mass
405.992739 Da
Topological polar surface area
65.4 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
3
Covalent units
2
Defined stereocentres
0

Also known as

ThiomersalThiomersalateMercurothiolateMERTHIOLATESodium merthiolateThimerosalateThimerosalumThimerosol
16 more reported names
ThimersalateThiomersalatSodium ethylmercurithiosalicylateThiomersalumMerfaminMertorganMerzoninTiomersalTiomersaleEstivinMerpholMercurothiolatumAeroaid sprayMerzonin sodiumMerthiolate saltEthylmercurithiosalicylate sodium
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 62-38-4
CAS 62-38-4PubChem CID 16682730

Phenylmercuric Acetate

IUPAC name
acetyloxy(phenyl)mercury
Molecular formula
C8H8HgO2
Molecular weight
336.74 g/mol
Exact mass
338.023073 Da
Topological polar surface area
26.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

phenylmercury acetateacetoxyphenylmercuryDyanacideGallotoxHostaquikLiquipheneMercuronMersolite
16 more reported names
NeantinaNorformsNylmeratePrograminQuicksanTrigosanVerdasanAnticonKwiksanMeracenPhenmadZiarnikBufenFemmaScutlPhix
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 6273-99-0
CAS 6273-99-0PubChem CID 16683655

Mercury, [mu-[orthoborato(2-)-O:O']]diphenyldi-

IUPAC name
[hydroxy(phenylmercuriooxy)boranyl]oxy-phenylmercury
Molecular formula
C12H11BHg2O3
Molecular weight
615.21 g/mol
Exact mass
616.019095 Da
Topological polar surface area
38.7 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

Mercury, [.mu.-[orthoborato(2-)-O:O']]diphenyldi-Mercury, (mu-(orthoborato(2-)-O:O'))diphenyldi-MercurylMersolite 90EINECS 228-465-7AI3-60045(mu-(Orthoborato(2-)-O:O'))diphenyldimercuryMercury, [.mu.-(hydrogen orthoborato)]diphenyldi-
4 more reported names
NSC 35683NSC-35683Mercury, (u-(orthoborato(2-)-O:O'))diphenyldi-(mu-Hydrogen-kappaO:kappaO' borato)diphenyldimercury
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 7439-97-6
CAS 7439-97-6PubChem CID 23931

Mercury

IUPAC name
mercury
Molecular formula
Hg
Molecular weight
200.59 g/mol
Exact mass
201.970644 Da
Topological polar surface area
0.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
0
Covalent units
1
Defined stereocentres
0

Also known as

QuicksilverHydrargyrumLiquid silverMetallic mercuryQuecksilberMercureMercurioColloidal mercury
16 more reported names
KwikMercurius vivusMercury, elementalMercury metalHgNCI-C60399MERCURY ELEMENTFXS1BY2PGLCHEBI:16170CHEBI:25195Dietary MercuryMercury metal: Colloidal mercuryMercurius 12XMercurius 21XMercurius vivus 8Mercurius vivus 6X
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 94-43-9
CAS 94-43-9PubChem CID 16682929

Phenylmercury benzoate

IUPAC name
benzoyloxy(phenyl)mercury
Molecular formula
C13H10HgO2
Molecular weight
398.81 g/mol
Exact mass
400.038723 Da
Topological polar surface area
26.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

PHENYLMERCURIC BENZOATE(Benzoato-O)phenylmercuryUNII-CHY7T9AM0WCHY7T9AM0WMercury, (benzoato)phenyl-EINECS 202-331-8NSC 84248NSC-84248
6 more reported names
RefChem:173089MERCURY, (BENZOYLOXY)PHENYL-Phenyl mercuric benzoateMercury, (benzoato-O)phenyl-Phenyl Mercury Benzoate(Benzoato-kappaO)phenylmercury
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

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Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

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FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

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ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

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Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

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NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

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OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

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US EPA CompTox CTX APIs

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

Open official Decision