PUERARIN

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence

Markets checked

13

Markets with evidence

0

Evidence gaps

13

Resolved identifiers

1

Resolved substance identity

CAS:3681-99-0

Ingredient index records:

PUERARIN

Cosmetic functions: ANTIOXIDANT

4H-1-Benzopyran-4-one, 8-beta-D-glucopyranosyl-7-hydroxy-3-(4-hydroxyphenyl)-

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1 matched or reported name

PUERARIN

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name PUERARIN.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 3681-99-0

CAS 3681-99-0PubChem CID 5281807

Puerarin is a hydroxyisoflavone that is isoflavone substituted by hydroxy groups at positions 7 and 4' and a beta-D-glucopyranosyl residue at position 8 via a C-glycosidic linkage. It has a role as an autophagy inducer, a ferroptosis inhibitor, an antioxidant, an antipyretic, an anti-inflammatory agent, a plant metabolite and a cardioprotective agent. It is a C-glycosyl compound and a hydroxyisoflavone. It is functionally related to an isoflavone. It is a conjugate acid of a puerarin(1-). — ChEBI

IUPAC name: 7-hydroxy-3-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one

Molecular formula: C21H20O9
Molecular weight: 416.4 g/mol
Exact mass: 416.11073221 Da
XLogP3: 0.0
Topological polar surface area: 157.0 Å²
Hydrogen-bond donors: 6
Hydrogen-bond acceptors: 9
Covalent units: 1
Defined stereocentres: 5

Also known as

KakoneinDaidzein-8-C-glucosideDaidzein 8-c-glucosidePuerarin 80 mmCHEBI:8633NPI 031GZ9W8997416NSC-380711

16 more reported names

4H-1-Benzopyran-4-one, 8-beta-D-glucopyranosyl-7-hydroxy-3-(4-hydroxyphenyl)-7-hydroxy-3-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]chromen-4-one7-hydroxy-3-(4-hydroxyphenyl)-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)chromen-4-one7-hydroxy-3-(4-hydroxyphenyl)-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl)chromen-4-oneRefChem:8703067-hydroxy-3-(4-hydroxyphenyl)-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-oneAC1NQZ4N7,4'-Dihydroxy-8-C-glucosylisoflavoneBRN 0064198BIDD:ER01018-(beta-D-Glucopyranosyl)-4',7-dihydroxyisoflavone8-beta-D-Glucopyranosyl-7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-onePuerarin, analytical standard7-hydroxy-3-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-4H-chromen-4-one(1S)-1,5-anhydro-1-[7-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-8-yl]-D-glucitol7-hydroxy-3-(4-hydroxyphenyl)-8-[(3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one

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External database identifiers

ChEBI:CHEBI:8633
ChEMBL:CHEMBL486386
EPA DTXSID:DTXSID30958020
PubMed:40995625
PubMed:37865300
PubMed:36527706
PubMed:35331853
PubMed:34897960
PubMed:34217736
PubMed:33404196
PubMed:33155599
PubMed:32763437
PubMed:31273855
PubMed:30672062
PubMed:27796870

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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