CAS 100-79-8PubChem CID 7528
Solketal
- IUPAC name
- (2,2-dimethyl-1,3-dioxolan-4-yl)methanol
- Molecular formula
- C6H12O3
- Molecular weight
- 132.16 g/mol
- Exact mass
- 132.078644241 Da
- XLogP3
- -0.2
- Topological polar surface area
- 38.7 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 3
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
2,2-Dimethyl-1,3-dioxolane-4-methanolGlycerolacetoneGlycerol dimethylketalDioxolanIsopropylidene glycerolGlycerol acetonide2,3-Isopropylideneglycerol1,3-Dioxolane-4-methanol, 2,2-dimethyl-
16 more reported names
Acetone monoglycerol ketalAcetone glycerolGlycerinisopropylidene ether2,3-O-Isopropylideneglycerol2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolaneAcetone, cyclic (hydroxymethyl)ethylene acetal3XK098O8ZWNSC-597202,3-Isopropylidene-sn-glycerolRefChem:441233202-888-7DL-1,2-Isopropylideneglycerol1,2-O-Isopropylideneglycerol1,2-Isopropylideneglycerol2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxacyclopentane1,2-Isopropylideneglycerin
External database identifiers
Evidence from additional scientific databases
NIH PubChem PUG-View
Exact identifier match7528
Attributed physical-property, hazard, environmental and use annotations.
- Boiling Point: 188-189 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Boiling Point: 75 °C @760 [mm Hg] Source: PAC Chemical Database, U.S. Department of Energy
- Density: Relative density (water = 1): 1.06 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Density: 1.065 @25 °C Source: PAC Chemical Database, U.S. Department of Energy
- Flash Point: 80 °C c.c. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: -26.4 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Physical Description: CBI; Liquid; Liquid; Other Solid Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Nearly odorless liquid; [Merck Index] Colorless oily liquid; Odorless; [ICSC] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: ODOURLESS OILY COLOURLESS LIQUID. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Solubility: Solubility in water: miscible Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Vapor Pressure: 107.0 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Vapor Pressure: 70 [mm Hg] @20 °C Source: PAC Chemical Database, U.S. Department of Energy
- Exposure Routes: The substance can be absorbed into the body by inhalation of its aerosol. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Note: This chemical does not meet GHS hazard criteria for 2% (7 of 353) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H315 (14.7%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (83.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H411 (14.7%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264, P264+P265, P273, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, P362+P364, P391, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 353 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 7 of 353 reports by companies.; There are 5 notifications provided by 346 of 353 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Consumer Uses: Fragrance; Not Known or Reasonably Ascertainable; Solvent Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Fragrance; Solvent; Monomers Source: EPA Chemical Data Reporting (CDR)
- Sources/Uses: Used as solvent, plasticizer, and pharmaceutical aid (solubilizing and suspending agent); [Merck Index] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| EMBL-EBI ChEBI | No exact record | 2026-08-31 |
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.