ICARISIDE II

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence

Markets checked

13

Markets with evidence

0

Evidence gaps

13

Resolved identifiers

1

Resolved substance identity

CAS:113558-15-9

Ingredient index records:

ICARISIDE II

Cosmetic functions: ANTIOXIDANT, BLEACHING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

3-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-5,7-dihydroxy-2-(4-Methoxyphenyl)-8-(3-Methyl-2-Buteny-1-yl)-

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1 matched or reported name

ICARISIDE II

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name ICARISIDE II.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 113558-15-9

CAS 113558-15-9PubChem CID 5488822

Icariside II is a glycosyloxyflavone that is 3,5,7-trihydroxy-4'-methoxy-8-prenylflavone in which the hydroxy group at position 3 has been converted into its alpha-L-rhamnopyranoside. It has a role as an antineoplastic agent, an anti-inflammatory agent, an apoptosis inducer and a plant metabolite. It is functionally related to an alpha-L-rhamnopyranose. — ChEBI

IUPAC name: 5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one

Molecular formula: C27H30O10
Molecular weight: 514.5 g/mol
Exact mass: 514.18389715 Da
XLogP3: 3.5
Topological polar surface area: 155.0 Å²
Hydrogen-bond donors: 5
Hydrogen-bond acceptors: 10
Covalent units: 1
Defined stereocentres: 5

Also known as

Baohuoside IICARISID IICHEBI:826193,5,7-Trihydroxy-4'-methoxyl-8-prenylflavone-3-O-rhamnopyranoside4H-1-Benzopyran-4-one, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-3-((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl)oxychromen-4-oneRefChem:9232685,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-3-((2S,3S,5R)-3,4,5-trihydroxy-6-methyloxan-2-yl)oxychromen-4-one

16 more reported names

BAOHUOSIDEIBaohuoside-I4H-1-Benzopyran-4-one, 3-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-5,7-Dihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}-4H-chromen-4-oneBaohuoside 13-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-onebaohuside IAMY496Icariin-IIBaohuoside I (Standard)Icaritin-3-O-alpha-rhamnosideHY-N0011RIcarisid II - Bio-X trade mark2h44GLXC-13027

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External database identifiers

ChEBI:CHEBI:82619
ChEMBL:CHEMBL560116
EPA DTXSID:DTXSID40150457
PubMed:35802278
PubMed:32945196
PubMed:31658364
PubMed:25119583
PubMed:22687635
PubMed:19289254
PubMed:17764702

Evidence from additional scientific databases

NIH PubChem PUG-View

Exact identifier match5488822

Attributed physical-property, hazard, environmental and use annotations.

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status

Source	Result	Checked
NIH PubChem PUG-View	Exact match	2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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