Skip to main content
CosIng Checker
CosIng Checker
EU cosmetic ingredients, restrictions and safety
Login
Official EU label nameGlossary entry 11351

GLYCYRRHETINIC ACID

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
2

Resolved substance identity

CAS:471-53-4
EC:207-444-6
Ingredient index records:
GLYCYRRHETINIC ACID
Cosmetic functions: SKIN CONDITIONING

Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3.beta., 20.beta.)-

Open full local profile
2 matched or reported names
GLYCYRRHETINIC ACIDenoxolone

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name GLYCYRRHETINIC ACID.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

Check the markets and their sourcesSearch every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 471-53-4
CAS 471-53-4PubChem CID 10114

Glycyrrhetinic Acid

Glycyrrhetinic acid is a pentacyclic triterpenoid that is olean-12-ene substituted by a hydroxy group at position 3, an oxo group at position 11 and a carboxy group at position 30. It has a role as an immunomodulator and a plant metabolite. It is a pentacyclic triterpenoid, a hydroxy monocarboxylic acid and a cyclic terpene ketone. It is a conjugate acid of a glycyrrhetinate. It derives from a hydride of an oleanane. — ChEBI

IUPAC name
(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid
Molecular formula
C30H46O4
Molecular weight
470.7 g/mol
Exact mass
470.33960994 Da
XLogP3
6.4
Topological polar surface area
74.6 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
9

Also known as

enoxoloneGlycyrrhetic acidUralenic acid18-beta-Glycyrrhetinic acidEnoxolona3beta-Hydroxy-11-oxoolean-12-en-30-oic acidEnoxolonumRhetinic Acid
16 more reported names
NSC-353473-beta-Hydroxy-11-oxoolean-12-en-30-oic acidP540XA09DRJintanCHEBI:30853Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3beta,20beta)-Glyciram(3beta,20beta)-3-Hydroxy-11-oxoolean-12-en-29-oic acidAcid, RhetinicAcid, UralenicAcid, GlycyrrheticAcid, Glycyrrhetinic12, PoRefChem:35616D03AX10(2S,4AS,6AS,6BR,10S,12AS)-10-HYDROXY-2,4A,6A,6B,9,9,12A-HEPTAMETHYL-13-OXO-3,4,5,6,7,8,8A,10,11,12,12B,14B-DODECAHYDRO-1H-PICENE-2-CARBOXYLIC ACID
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

Take this record further

Screen in a formulaOpen standalone comparison

Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

Open official Decision