
Nicotinamide
Nicotinamide is a pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group. It has a role as a geroprotector, an antioxidant, a cofactor, a metabolite, an EC 3.5.1.98 (histone deacetylase) inhibitor, an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor, a neuroprotective agent, an anti-inflammatory agent, a Sir2 inhibitor, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human urinary metabolite. It is a vitamin B3, a pyridinecarboxamide and a pyridine alkaloid. It is functionally related to a nicotinic acid. — ChEBI
- IUPAC name
- pyridine-3-carboxamide
- Molecular formula
- C6H6N2O
- Molecular weight
- 122.12 g/mol
- Exact mass
- 122.048012819 Da
- XLogP3
- -0.4
- Topological polar surface area
- 56.0 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 2
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:17154
- ChEMBL:CHEMBL1140
- EPA DTXSID:DTXSID2020929
- PubMed:29968805
- PubMed:23100645
- PubMed:23100637
- PubMed:23089640
- PubMed:23083076
- PubMed:23082226
- PubMed:23053940
- PubMed:23043222
- PubMed:23040396
- PubMed:23036333
- PubMed:23036087
- PubMed:23033175
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.