Why does CAS 85-79-0 appear in more than one EU cosmetic annex?

A substance identified by CAS 85-79-0 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

How do I check if my formula contains a substance with CAS 85-79-0?

Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 85-79-0 to screen it directly, then review every linked annex record and supplier document.

CAS 1 record

CAS 85-79-0

Q: How do I use CAS 85-79-0 for compliance screening?

Cross-reference CAS 85-79-0 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 85-79-0 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

Check this CAS number Browse annexes

Chemical identity and properties

PubChem 2D chemical structure for CAS 85-79-0

CAS 85-79-0PubChem CID 3025

Dibucaine

Cinchocaine is a monocarboxylic acid amide that is the 2-(diethylamino)ethyl amide of 2-butoxyquinoline-4-carboxylic acid. One of the most potent and toxic of the long-acting local anesthetics, its parenteral use was restricted to spinal anesthesia. It is now generally only used (usually as the hydrochloride) in creams and ointments and in suppositories for temporary relief of pain and itching associated with skin and anorectal conditions. It has a role as a topical anaesthetic. It is a monocarboxylic acid amide, an aromatic ether and a tertiary amino compound. — ChEBI

IUPAC name: 2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide

Molecular formula: C20H29N3O2
Molecular weight: 343.5 g/mol
Exact mass: 343.22597718 Da
XLogP3: 4.4
Topological polar surface area: 54.5 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

CinchocaineNupercainalDermacaineDibucaine BaseDibucainCinchocainumCincocainaCincocainio

16 more reported names

Dibucaine [USP]2-Butoxyquinoline-4-carboxylic acid diethylaminoethylamide2-butoxy-N-(2-(diethylamino)ethyl)quinoline-4-carboxamideDibucaine (USP)2-Butoxy-N-(2-(diethylamino)ethyl)cinchoninamide2-Butoxy-N-(beta-diethylaminoethyl)cinchoninamide2-N-Butoxy-N-(2-diethylaminoethyl)cinchoninamideN-(2-(Diethylamino)ethyl)-2-butoxycinchoninamidealpha-Butyloxycinchoninic acid diethylethylenediamidealpha-Butyloxycinchonic acid-gamma-diethylethylenediamine2-Butoxy-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamideDibucaine 1%L6JW2TJG99NSC-1590554-Quinolinecarboxamide, 2-butoxy-N-[2-(diethylamino)ethyl]-2-Butoxy-N-[2-(diethylamino)ethyl]cinchoninamide

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:247956
ChEMBL:CHEMBL1086
EPA DTXSID:DTXSID3045271
PubMed:32795450
PubMed:28551711
PubMed:27109752
PubMed:25947082
PubMed:25455453
PubMed:22842001
PubMed:22753757
PubMed:22653014
PubMed:22558504
PubMed:22529904
PubMed:22504686
PubMed:22471523

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 85-79-0

1 total

Annex

Entry

129

Cinchocaine (INN) and its salts

201-632-1

How CAS 85-79-0 is used on this site

CAS 85-79-0 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 85-79-0 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 85-79-0 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

The INCI Checker accepts ingredient names, CAS numbers and EC numbers. Check this CAS number directly, then verify the result against supplier specification sheets and every linked annex condition.

Check this CAS number

Tools & next steps

Check your formula

Scan a full INCI list, then use CAS 85-79-0 to cross-check any supplier documents behind the matched substances.

INCI Checker

Browse annexes

Browse all EU cosmetic regulation annexes by category.

All annexes

Search by name

Search for INCI names, aliases or related identifiers that sit alongside CAS 85-79-0 in your documentation.