Why does CAS 8005-03-6 appear in more than one EU cosmetic annex?

A substance identified by CAS 8005-03-6 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

How do I check if my formula contains a substance with CAS 8005-03-6?

Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 8005-03-6 to screen it directly, then review every linked annex record and supplier document.

CAS 2 records

CAS 8005-03-6

Q: How do I use CAS 8005-03-6 for compliance screening?

Cross-reference CAS 8005-03-6 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 8005-03-6 matches 2 EU annex records across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 8005-03-6

CAS 8005-03-6PubChem CID 135442942

2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-3-(2-(4-nitrophenyl)diazenyl)-6-(2-phenyldiazenyl)-, sodium salt (1:?)

Amido Black 10B is an organic sodium salt resulting from the formal condensation of Amido Black 10B (acid form) with two equivalents of sodium hydroxide. It has a role as a histological dye. It contains a 4-amino-5-hydroxy-3-[(p-nitrophenyl)azo]-6-(phenylazo)-naphthalene-2,7-disulfonate. — ChEBI

IUPAC name: disodium;4-amino-5-hydroxy-3-[(4-nitrophenyl)diazenyl]-6-phenyldiazenylnaphthalene-2,7-disulfonate

Molecular formula: C22H14N6Na2O9S2
Molecular weight: 616.5 g/mol
Exact mass: 616.00590696 Da
Topological polar surface area: 273.0 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 14
Covalent units: 3
Defined stereocentres: 0

Also known as

4-Amino-5-hydroxy-3-((4-nitrophenyl)azo)-6-(phenylazo)naphthalene-2,7-disulphonic acid, sodium saltRefChem:446195280-105-8ACID BLACK 11064-48-8Naphthol Blue BlackAmido Black 10BAcid black 2

16 more reported names

Buffalo Black NBRC.I. Acid Black 1NIGROSINEAmidoschwarzAmido blackC.I. Acid Black 1, disodium saltAcidal Black 10BNaphthol Blue Black BAcidal Navy Blue 3BRAcid Blue BlackAcid Blue-BlackC.I. 20470Sandopel Blue PBoruta Black ASolar Blue BlackAcid Black H

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:86230
EPA DTXSID:DTXSID1020934
EPA DTXSID:DTXSID1024415

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 8005-03-6

2 total

Annex

Entry

1359

Nigrosine (CI 50420) when used as a substance in hair dye products

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Annex

Entry

CI 50420

Sulfonated nigrosine color

—

Max concentration

How CAS 8005-03-6 is used on this site

CAS 8005-03-6 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 2 EU annex records share this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 8005-03-6 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 8005-03-6 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

The INCI Checker accepts ingredient names, CAS numbers and EC numbers. Check this CAS number directly, then verify the result against supplier specification sheets and every linked annex condition.

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