Why does CAS 7683-59-2 appear in more than one EU cosmetic annex?

A substance identified by CAS 7683-59-2 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

How do I check if my formula contains a substance with CAS 7683-59-2?

Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 7683-59-2 to screen it directly, then review every linked annex record and supplier document.

CAS 1 record

CAS 7683-59-2

Q: How do I use CAS 7683-59-2 for compliance screening?

Cross-reference CAS 7683-59-2 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 7683-59-2 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 7683-59-2

CAS 7683-59-2PubChem CID 3779

Isoproterenol

Isoprenaline is a secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders. It has a role as a beta-adrenergic agonist, a bronchodilator agent, a sympathomimetic agent and a cardiotonic drug. It is a member of catechols, a secondary alcohol and a secondary amino compound. — ChEBI

IUPAC name: 4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol

Molecular formula: C11H17NO3
Molecular weight: 211.26 g/mol
Exact mass: 211.12084340 Da
XLogP3: -0.6
Topological polar surface area: 72.7 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

IsoprenalineIsopropydrinAludrineNovodrinAsiprenolAssiprenolBellasthmanIsoprenalin

16 more reported names

RespifralAsmalarNeodrenalProternolneo-EpinineIsonorinIsoreninSaventrineIsopropylarterenolN-IsopropylnoradrenalineIsopropyladrenalineN-IsopropylnorepinephrineIsuprenIsopropylnorepinephrineVapo-N-isoIsopropylnoradrenaline

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:64317
ChEMBL:CHEMBL434
EPA DTXSID:DTXSID4023175
PubMed:23084196
PubMed:23050266
PubMed:22750028
PubMed:22573921
PubMed:22493922
PubMed:22391854
PubMed:22340511
PubMed:22289617
PubMed:22233780
PubMed:22164209
PubMed:22033422
PubMed:22021992

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 7683-59-2

1 total

Annex

Entry

Isoprenaline (INN)

231-687-7

How CAS 7683-59-2 is used on this site

CAS 7683-59-2 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 7683-59-2 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 7683-59-2 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

The INCI Checker accepts ingredient names, CAS numbers and EC numbers. Check this CAS number directly, then verify the result against supplier specification sheets and every linked annex condition.

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