Why does CAS 74578-10-2 appear in more than one EU cosmetic annex?

A substance identified by CAS 74578-10-2 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

How do I check if my formula contains a substance with CAS 74578-10-2?

Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 74578-10-2 to screen it directly, then review every linked annex record and supplier document.

CAS 1 record

CAS 74578-10-2

Q: How do I use CAS 74578-10-2 for compliance screening?

Cross-reference CAS 74578-10-2 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 74578-10-2 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 74578-10-2

CAS 74578-10-2PubChem CID 173294

Benzenamine, 4-((2,6-dichlorophenyl)(4-imino-3,5-dimethyl-2,5-cyclohexadien-1-ylidene)methyl)-2,6-dimethyl-, phosphate (1:1)

IUPAC name: 4-[(2,6-dichlorophenyl)-(4-imino-3,5-dimethylcyclohexa-2,5-dien-1-ylidene)methyl]-2,6-dimethylaniline;phosphoric acid

Molecular formula: C23H25Cl2N2O4P
Molecular weight: 495.3 g/mol
Exact mass: 494.0928997 Da
Topological polar surface area: 128.0 Å²
Hydrogen-bond donors: 5
Hydrogen-bond acceptors: 6
Covalent units: 2
Defined stereocentres: 0

Also known as

HC Blue No. 1562LA9436UJBenzenamine, 4-[(2,6-dichlorophenyl)(4-imino-3,5-dimethyl-2,5-cyclohexadien-1-ylidene)methyl]-2,6-dimethyl-, phosphate (1:1)Basic Blue 77EINECS 277-929-5UNII-62LA9436UJJade BlueGardex Jade Blue

10 more reported names

HC Azul 15HC Bleu 15Basic Blue 77 phosphateHC Blu 15RJKYUPXJBBSRML-UHFFFAOYSA-N2,6-Xylidine, 4-(2,6-dichloro-alpha-(4-imino-3,5-dimethyl-2,5-cyclohexadien-1-ylidene)benzyl)-, dihydrogen phosphateWR 8021784-((2,6-Dichlorophenyl)(4-imino-3,5-dimethylcyclohexa-2,5-dien-1-ylidene)methyl)-2,6-dimethylanilinephosphate4-((2,6-Dichlorophenyl)(4-imino-3,5-dimethylcyclohexa-2,5-dien-1-ylidene)methyl)-2,6-xylidine phosphate (1:1)Phosphoric acid--4-[(2,6-dichlorophenyl)(4-imino-3,5-dimethylcyclohexa-2,5-dien-1-ylidene)methyl]-2,6-dimethylaniline (1/1)

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID3072793

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 74578-10-2

1 total

Annex

III

Entry

289

HC BLUE NO 15

Phosphoric acid compound with 4-[(2,6-dichlorophenyl) (4-imino- 3,5-dimethyl-2,5- cyclohexadien-1- ylidene) methyl]- 2,6-dimethylaniline (1:1)

(a) To be printed on the label: The mixing ratio Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary "black h…

277-929-5

Max concentration

How CAS 74578-10-2 is used on this site

CAS 74578-10-2 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 74578-10-2 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 74578-10-2 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

The INCI Checker accepts ingredient names, CAS numbers and EC numbers. Check this CAS number directly, then verify the result against supplier specification sheets and every linked annex condition.

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