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CAS 7365-45-9

CAS 7365-45-9 matches 0 EU annex records across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 7365-45-9
CAS 7365-45-9PubChem CID 23831

4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid

2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid is a HEPES that is ethanesulfonic acid in which one of the methyl hydrogens is replaced by a 4-(2-hydroxyethyl)piperazin-1-yl group. A Good's buffer substance, pKa = 7.55 at 20 C. It is an organosulfonic acid and a HEPES. It is a conjugate acid of a 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonate. It is a tautomer of a 2-[4-(2-hydroxyethyl)piperazin-4-ium-1-yl]ethanesulfonate. — ChEBI

IUPAC name
2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid
Molecular formula
C8H18N2O4S
Molecular weight
238.31 g/mol
Exact mass
238.09872823 Da
XLogP3
-4.0
Topological polar surface area
89.5 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
0

Also known as

HEPES1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-HEPES solution4-(2-Hydroxyethyl)-1-piperazineethane sulfonic acidRWW266YE9ICHEBI:42334hydroxyethylpiperazine ethane sulfonic acidNSC-166663
16 more reported names
Monosodium Salt, HEPESSalt, HEPES MonosodiumN 2 Hydroxyethylpiperazine N' 2' ethanesulfonic AcidN-2-Hydroxyethylpiperazine-N'-2'-ethanesulfonic AcidRefChem:783545CHEBI:46756Hydroxyethyl Piperazine Ethanesulfonic Acid Solution230-907-92-(4-(2-Hydroxyethyl)piperazin-1-yl)ethanesulfonic acid4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acidN-2-Hydroxyethylpiperazine-N'-ethanesulfonateN-2-Hydroxyethylpiperazine-N'-ethanesulfonic acidN-2-Hydroxyethylpiperazine-N-ethane sulfonic acidNSC 166663N-2-Hydroxyethylpiperazine N',2'-ethanesulfonic acid
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External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 7365-45-9

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How CAS 7365-45-9 is used on this site

CAS 7365-45-9 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 0 EU annex records share this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 7365-45-9 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.