Why does CAS 67129-08-2 appear in more than one EU cosmetic annex?

A substance identified by CAS 67129-08-2 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

How do I check if my formula contains a substance with CAS 67129-08-2?

Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 67129-08-2 to screen it directly, then review every linked annex record and supplier document.

CAS 1 record

CAS 67129-08-2

Q: How do I use CAS 67129-08-2 for compliance screening?

Cross-reference CAS 67129-08-2 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 67129-08-2 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 67129-08-2

CAS 67129-08-2PubChem CID 49384

Metazachlor

Metazachlor is an organochlorine compound that is 2-chloroacetamide substituted by a 2,6-dimethylphenyl and a (1H-pyrazol-1-ylmethyl) group at the nitrogen atom. It has a role as a herbicide, a xenobiotic and an environmental contaminant. It is a member of pyrazoles, an organochlorine compound and an aromatic amide. — ChEBI

IUPAC name: 2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide

Molecular formula: C14H16ClN3O
Molecular weight: 277.75 g/mol
Exact mass: 277.0981898 Da
XLogP3: 2.7
Topological polar surface area: 38.1 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

2-Chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide2-Chloro-N-(pyrazol-1-ylmethyl)acet-2',6'-xylidideTPY2K437O4CHEBI:6798RefChem:156821266-583-0Butisan SMetazachlore

16 more reported names

N-((1H-Pyrazol-1-yl)methyl)-2-chloro-N-(2,6-dimethylphenyl)acetamideBAS 479HMetazachlor [BSI:ISO]2-Chloro-N-(2,6-dimethylphenyl)-N-[(1H-pyrazol-1-yl)methyl]acetamideAcetamide, 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)-2-Chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)-acetamidePreeMetazachlore [ISO-French]EINECS 266-583-0BRN 0621550UNII-TPY2K437O4MetazochlorMETAZACHLOR [MI]METAZACHLOR [ISO]5-23-04-00126 (Beilstein Handbook Reference)US9138393, Metazachlor

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:6798
ChEMBL:CHEMBL2272118
EPA DTXSID:DTXSID4058156
PubMed:31465819
PubMed:22480233
PubMed:22284369
PubMed:22098937
PubMed:21807215
PubMed:21531461
PubMed:21509808
PubMed:21484246
PubMed:20390937
PubMed:19709252
PubMed:19071262
PubMed:18433974

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 67129-08-2

1 total

Annex

Entry

1552

Metazachlor (ISO); 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide

266-583-0

CMR

How CAS 67129-08-2 is used on this site

CAS 67129-08-2 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 67129-08-2 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 67129-08-2 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

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