Why does CAS 56073-07-5 appear in more than one EU cosmetic annex?

A substance identified by CAS 56073-07-5 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

How do I check if my formula contains a substance with CAS 56073-07-5?

Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 56073-07-5 to screen it directly, then review every linked annex record and supplier document.

CAS 1 record

CAS 56073-07-5

Q: How do I use CAS 56073-07-5 for compliance screening?

Cross-reference CAS 56073-07-5 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 56073-07-5 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 56073-07-5

CAS 56073-07-5PubChem CID 54676884

Difenacoum

Difenacoum is a member of benzenes, a member of naphthalenes and a ring assembly. — ChEBI

IUPAC name: 4-hydroxy-3-[3-(4-phenylphenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]chromen-2-one

Molecular formula: C31H24O3
Molecular weight: 444.5 g/mol
Exact mass: 444.17254462 Da
XLogP3: 6.9
Topological polar surface area: 46.5 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

NeosorexaDiphenacoumDifenakumNeosorexa PP580WBA 8107SBA3K9U26B3-(3-Biphenyl-4-yl-1,2,3,4-tetrahydro-1-naphthyl)-4-hydroxycoumarin2H-1-Benzopyran-2-one, 3-(3-(1,1'-biphenyl)-4-yl-1,2,3,4-tetrahydro-1-naphthalenyl)-4-hydroxy-

16 more reported names

3-(3-(1,1'-Biphenyl)-4-yl-1,2,3,4-tetrahydro-1-naphthalenyl)-4-hydroxy-2H-1-benzopyran-2-oneCOUMARIN, 3-(3-(4-BIPHENYLYL)-1,2,3,4-TETRAHYDRO-1-NAPHTHYL)-4-HYDROXY-3-(3-p-Diphenyl-1,2,3,4-tetrahydronaphth-1-yl)-4-hydroxycoumarin2H-1-Benzopyran-2-one, 3-(3-[1,1'-biphenyl]-4-yl-1,2,3,4-tetrahydro-1-naphthalenyl)-4-hydroxy-RefChem:1335482-hydroxy-3-(3-(4-phenylphenyl)-1,2,3,4-tetrahydronaphthalen-1-yl)-4H-chromen-4-one259-978-4RatakPP, ratDifenakum [Czech]Difenacoum [BSI:ISO]Difenacoum [ISO]HSDB 6609C31H24O3EINECS 259-978-4UNII-SBA3K9U26B

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:80743
ChEMBL:CHEMBL5416849
EPA DTXSID:DTXSID2058128
PubMed:31595789
PubMed:29155484
PubMed:27117082
PubMed:23108575
PubMed:22767114
PubMed:22588365
PubMed:22379046
PubMed:21898757
PubMed:21477845
PubMed:21268531
PubMed:21165290
PubMed:20529461

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 56073-07-5

1 total

Annex

Entry

1628

Difenacoum (ISO); 3-(3- biphenyl-4-yl-1,2,3,4- tetrahydro-1-naphthyl)- 4-hydroxycoumarin

259-978-4

CMR

How CAS 56073-07-5 is used on this site

CAS 56073-07-5 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 56073-07-5 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 56073-07-5 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

The INCI Checker accepts ingredient names, CAS numbers and EC numbers. Check this CAS number directly, then verify the result against supplier specification sheets and every linked annex condition.

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