
Clobetasone
Clobetasone is a corticosteroid that is often employed topically as a treatment for a variety of conditions such as eczema, psoriasis, various forms of dermatitis, and also for certain ophthalmologic conditions. Topical clobetasone butyrate has shown minimal suppression of the Hypothalamic-pituitary-adrenal axis. — DrugBank
- IUPAC name
- (8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-17-hydroxy-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthrene-3,11-dione
- Molecular formula
- C22H26ClFO4
- Molecular weight
- 408.9 g/mol
- Exact mass
- 408.1503652 Da
- XLogP3
- 2.6
- Topological polar surface area
- 71.4 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 5
- Covalent units
- 1
- Defined stereocentres
- 7
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:177795
- EPA DTXSID:DTXSID601023875
- PubMed:22536546
- PubMed:20017943
- PubMed:16496263
- PubMed:15948981
- PubMed:15869538
- PubMed:15758802
- PubMed:15209961
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.