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CAS 500-38-9

CAS 500-38-9 matches 0 EU annex records across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 500-38-9
CAS 500-38-9PubChem CID 4534

Nordihydroguaretic acid

Nordihydroguaiaretic acid is a tetrol that is butane which is substituted at positions 2 and 3 by 3,4-dihydroxybenzyl groups. Masoprocol, the meso-form found in the leaves of the creosote bush (Larrea divaricata), is a potent lipoxygenase inhibitor. It has a role as a ferroptosis inhibitor, a geroprotector, an antioxidant and a plant metabolite. It is a lignan, a member of catechols and a tetrol. — ChEBI

IUPAC name
4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
Molecular formula
C18H22O4
Molecular weight
302.4 g/mol
Exact mass
302.15180918 Da
XLogP3
4.3
Topological polar surface area
80.9 Ų
Hydrogen-bond donors
4
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

2,3-bis(3,4-dihydroxybenzyl)butaneRefChem:854717NORDIHYDROGUAIARETIC ACIDNDGANorhydroguaiaretic acidNorguaiaretic acid, dihydro-1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-NSC 4291
16 more reported names
4,4'-(2,3-Dimethyltetramethylene)dipyrocatechol2,3-Bis(3,4-dihydroxyphenylmethyl)butanePyrocatechol, 4,4'-(2,3-dimethyltetramethylene)di-4,4'-(2,3-Dimethyl-1,4-butanediyl)bis(pyrocatechol)nordihydroguaiaretateCHEMBL52Butane, 1,4-bis(3,4-dihydroxyphenyl)-2,3-dimethyl-4,4'-(2,3-dimethylbutane-1,4-diyl)bis(benzene-1,2-diol)beta,gamma-Dimethyl-alpha,delta-bis(3,4-dihydroxyphenyl)butaneCHX 100; Masoprocol; meso-NDGA4,4'-(2,3-Dimethyl-1,4-butanediyl)bis-1,2-benzenediol4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diolNordihydroGuaiareticAcid-d6Nordihydro Guaiaretic Acid (mixture of diastereomers)4,4'-(2,3-dimethylbutane-1,4-diyl)dibenzene-1,2-diol4,4'-(2,3-Dimethylbutane-1,4-diyl)di(benzene-1,2-diol)
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External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 500-38-9

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How CAS 500-38-9 is used on this site

CAS 500-38-9 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 0 EU annex records share this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 500-38-9 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.