
Betulinic Acid
Betulinic acid is a pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-carboxy substituents. It is found in the bark and other plant parts of several species of plants including Syzygium claviflorum. It exhibits anti-HIV, antimalarial, antineoplastic and anti-inflammatory properties. It has a role as an antineoplastic agent, an antimalarial, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, an anti-HIV agent, an anti-inflammatory agent and a plant metabolite. It is a pentacyclic triterpenoid and a hydroxy monocarboxylic acid. It derives from a hydride of a lupane. — ChEBI
- IUPAC name
- (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
- Molecular formula
- C30H48O3
- Molecular weight
- 456.7 g/mol
- Exact mass
- 456.36034539 Da
- XLogP3
- 8.2
- Topological polar surface area
- 57.5 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 3
- Covalent units
- 1
- Defined stereocentres
- 10
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:3087
- ChEMBL:CHEMBL269277
- EPA DTXSID:DTXSID80861974
- PubMed:24623716
- PubMed:23821410
- PubMed:23399723
- PubMed:23122155
- PubMed:23122121
- PubMed:23114617
- PubMed:23112419
- PubMed:23085651
- PubMed:23056140
- PubMed:23019882
- PubMed:23017402
- PubMed:23017394
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.