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CAS 1 record

CAS 458-37-7

CAS 458-37-7 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

Chemical identity and properties

PubChem 2D chemical structure for CAS 458-37-7
CAS 458-37-7PubChem CID 969516

Curcumin

Curcumin is a beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa. It has a role as a geroprotector, a metabolite, a biological pigment, an antineoplastic agent, a flavouring agent, an antifungal agent, a lipoxygenase inhibitor, a dye, an iron chelator, an EC 1.1.1.21 (aldehyde reductase) inhibitor, a radical scavenger, a contraceptive drug, an EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor, a nutraceutical, an immunomodulator, a ligand, an EC 1.1.1.205 (IMP dehydrogenase) inhibitor, an EC 3.5.1.98 (histone deacetylase) inhibitor, a hepatoprotective agent, a neuroprotective agent, an EC 1.8.1.9 (thioredoxin reductase) inhibitor, an anti-inflammatory agent, an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor, a food colouring and an EC 1.1.1.25 (shikimate dehydrogenase) inhibitor. It is a polyphenol, an aromatic ether, an enone, a beta-diketone and a diarylheptanoid. It is functionally related to a trans-ferulic acid. ChEBI

IUPAC name
(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
Molecular formula
C21H20O6
Molecular weight
368.4 g/mol
Exact mass
368.12598835 Da
XLogP3
3.2
Topological polar surface area
93.1 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
0

Also known as

DiferuloylmethaneNatural yellow 3Kacha haldiCurcumin ICurcumaHaldarIndian saffronGelbwurz
16 more reported names
Yellow GingerSouchetHaidrHaladHaludTerra MeritaC.I. Natural Yellow 3Safran d'IndeYo-KinYellow puccoonDiferaloylmethaneCI Natural Yellow 3C.I. 75300JianghuangsuKurkuminNanoCurc
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 458-37-7

1 total
No records found for this CAS number.

How CAS 458-37-7 is used on this site

CAS 458-37-7 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 458-37-7 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.