Why does CAS 4403-90-1 appear in more than one EU cosmetic annex?

A substance identified by CAS 4403-90-1 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

How do I check if my formula contains a substance with CAS 4403-90-1?

Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 4403-90-1 to screen it directly, then review every linked annex record and supplier document.

CAS 2 records

CAS 4403-90-1

Q: How do I use CAS 4403-90-1 for compliance screening?

Cross-reference CAS 4403-90-1 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 4403-90-1 matches 2 EU annex records across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 4403-90-1

CAS 4403-90-1PubChem CID 20431

Acid Green 25

D & c green 5 appears as fine black or green powder. (NTP, 1992) — CAMEO Chemicals

IUPAC name: disodium;5-methyl-2-[[4-(4-methyl-2-sulfonatoanilino)-9,10-dioxoanthracen-1-yl]amino]benzenesulfonate

Molecular formula: C28H20N2Na2O8S2
Molecular weight: 622.6 g/mol
Exact mass: 622.04564651 Da
Topological polar surface area: 189.0 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 10
Covalent units: 3
Defined stereocentres: 0

Also known as

D&C Green No. 5Alizarin Cyanine Green FSolway Green GAErionyl Green GLAlizarine Green JAquamine Green GLAlizarine Green CEAlizarine Green CG

16 more reported names

Airedale Green ACGC.I. ACID GREEN 25Diachromate Green GErio Fast Green GSD & C Green No. 5Anthraquinone Green GNeutral Fast Green GNylosan Green CP-GLTertrochrome Green CGFenazo Fast Green AGFenazo Fast Green ANAcid Leather Green AGBucacid Fast Green GSDiacid Light Green GSEriosin Fast Green GLOrtol Green B

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID2024903

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 4403-90-1

2 total

Annex

III

Entry

290

ACID GREEN 25

Disodium 2,2′- (9,10-dioxoanthracene-1,4-diyldiimino)bis(5- methylsulphonate)

Hair dye substance in non-oxidative hair dye products

224-546-6

Max concentration

Annex

Entry

CI 61570

Disodium 2,2'-(9,10-dioxoanthracene-1,4-diyldiimino)bis(5-methylsulphonate)

224-546-6

How CAS 4403-90-1 is used on this site

CAS 4403-90-1 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 2 EU annex records share this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 4403-90-1 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 4403-90-1 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

The INCI Checker accepts ingredient names, CAS numbers and EC numbers. Check this CAS number directly, then verify the result against supplier specification sheets and every linked annex condition.

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Tools & next steps

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