Why does CAS 41483-43-6 appear in more than one EU cosmetic annex?

A substance identified by CAS 41483-43-6 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

How do I check if my formula contains a substance with CAS 41483-43-6?

Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 41483-43-6 to screen it directly, then review every linked annex record and supplier document.

CAS 1 record

CAS 41483-43-6

Q: How do I use CAS 41483-43-6 for compliance screening?

Cross-reference CAS 41483-43-6 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 41483-43-6 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 41483-43-6

CAS 41483-43-6PubChem CID 38884

Bupirimate

Bupirimate is a member of the class of aminopyrimidines that is 2-ethylaminopyrimidine carrying methyl, butyl and dimethylaminosulfooxy substituents at posiitons 4, 5 and 6 respectively. It has a role as an androgen antagonist and an antifungal agrochemical. It is an aminopyrimidine, a sulfamate ester, a secondary amino compound and a pyrimidine fungicide. — ChEBI

IUPAC name: [5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl] N,N-dimethylsulfamate

Molecular formula: C13H24N4O3S
Molecular weight: 316.42 g/mol
Exact mass: 316.15691181 Da
XLogP3: 2.7
Topological polar surface area: 92.8 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 7
Covalent units: 1
Defined stereocentres: 0

Also known as

NimrodPP588MCJ121RIOI5-Butyl-2-(ethylamino)-6-methyl-4-pyrimidinyl dimethylsulfamate2-Aethylamino-5-butyl-4-yl-dimethylsulfamatSulfamic acid, dimethyl-, 5-butyl-2-(ethylamino)-6-methyl-4-pyrimidinyl ester5-Butyl-2-ethylamino-6-methylpyrimidin-4-yl dimethylsulphamateDimethylsulfamic acid 5-butyl-2-(ethylamino)-6-methyl-4-pyrimidinyl ester

16 more reported names

CHEBI:81952Sulfamic acid, N,N-dimethyl-, ester with 5-butyl-2-ethylamino-6-methylpyrimidin-4-ol2-aminoethyl-5-butyl-4(N)-methylsulfonate-6-methylpyrimidineRefChem:121922Bupirimate, 90%5-Butyl-2-ethylamino-6-methylpyrimidin-4-yl dimethylsulfamate5-Butyl-2-ethylamino-6-methylpyrimidin-4-yldimethylsulphamateBupirimate [ANSI:BSI:ISO]5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamateEINECS 255-391-2Nanogen Index Code BPT (1-011)Bupirimate [ISO]BRN 0758056UNII-MCJ121RIOIBuprimatePP-588

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:81952
ChEMBL:CHEMBL3183902
EPA DTXSID:DTXSID6041688
PubMed:22467459
PubMed:21924250
PubMed:20736058
PubMed:17466998
PubMed:16565514
PubMed:16130755
PubMed:15844516
PubMed:15754777
PubMed:14700235
PubMed:11714287
PubMed:11407590

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 41483-43-6

1 total

Annex

Entry

1639

Bupirimate (ISO); 5-butyl-2-ethylamino-6- methylpyrimidin-4-yl dimethylsulfamate

255-391-2

CMR

How CAS 41483-43-6 is used on this site

CAS 41483-43-6 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 41483-43-6 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 41483-43-6 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

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