Why does CAS 375-85-9 appear in more than one EU cosmetic annex?

A substance identified by CAS 375-85-9 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

How do I check if my formula contains a substance with CAS 375-85-9?

Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 375-85-9 to screen it directly, then review every linked annex record and supplier document.

CAS 1 record

CAS 375-85-9

Q: How do I use CAS 375-85-9 for compliance screening?

Cross-reference CAS 375-85-9 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 375-85-9 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 375-85-9

CAS 375-85-9PubChem CID 67818

Perfluoroheptanoic acid

Perfluoroheptanoic acid is a fluoroalkanoic acid that is perfluorinated heptanoic acid. It has a role as a xenobiotic and an environmental contaminant. It is functionally related to a perfluoroheptane and a heptanoic acid. — ChEBI

IUPAC name: 2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoroheptanoic acid

Molecular formula: C7HF13O2
Molecular weight: 364.06 g/mol
Exact mass: 363.9768954 Da
XLogP3: 4.3
Topological polar surface area: 37.3 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 15
Covalent units: 1
Defined stereocentres: 0

Also known as

Tridecafluoroheptanoic acidPFHpAPerfluoroenanthic AcidPerfluoro-n-heptanoic acidHeptanoic acid, tridecafluoro-Tridecafluoro-1-heptanoic acid4Q4V9K363YCHEBI:35547

16 more reported names

PFHpA compoundTDFHA cpdC7-PFAPFHpA perfluoroheptanoic acidRefChem:171659206-798-9C7HF13O2PerfluoroheptanoicacidC6F13COOHPerfluoroheptanoic Acid High GradeEN300-1704061Heptanoic acid, 2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoro-4EIEINECS 206-798-9n-perfluoroheptanoic acidTridecafluoroenanthic Acid

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:35547
ChEMBL:CHEMBL172763
EPA DTXSID:DTXSID1037303
PubMed:41460158
PubMed:39933620
PubMed:39343156
PubMed:36436016
PubMed:36435305
PubMed:35337807
PubMed:35121066
PubMed:33984575
PubMed:33677611
PubMed:33220336
PubMed:28115241
PubMed:27572461

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 375-85-9

1 total

Annex

Entry

1705

Perfluoroheptanoic acid; tridecafluoroheptanoic acid

206-798-9

How CAS 375-85-9 is used on this site

CAS 375-85-9 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 375-85-9 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 375-85-9 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

The INCI Checker accepts ingredient names, CAS numbers and EC numbers. Check this CAS number directly, then verify the result against supplier specification sheets and every linked annex condition.

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Tools & next steps

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