CAS 22839-47-0PubChem CID 134601
Aspartame
Aspartame is a dipeptide obtained by formal condensation of the alpha-carboxy group of L-aspartic acid with the amino group of methyl L-phenylalaninate. Commonly used as an artificial sweetener. It has a role as a micronutrient, a xenobiotic, a sweetening agent, a nutraceutical, an EC 3.1.3.1 (alkaline phosphatase) inhibitor, an apoptosis inhibitor and an environmental contaminant. It is a methyl ester, a carboxylic acid and a dipeptide. It is functionally related to a L-aspartic acid and a methyl L-phenylalaninate. It is a tautomer of an aspartame zwitterion. — ChEBI
- IUPAC name
- (3S)-3-amino-4-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid
- Molecular formula
- C14H18N2O5
- Molecular weight
- 294.30 g/mol
- Exact mass
- 294.12157168 Da
- XLogP3
- -2.7
- Topological polar surface area
- 119.0 Ų
- Hydrogen-bond donors
- 3
- Hydrogen-bond acceptors
- 6
- Covalent units
- 1
- Defined stereocentres
- 2
Also known as
NutrasweetAsp-phe-omeAspartamAspartamoSweet dipeptideL-Aspartyl-L-phenylalanine methyl esterAspartamumDipeptide sweetener
16 more reported names
EqualMethyl aspartylphenylalanateAspartylphenylalanine methyl esterPal SweetSladexZero-calSC-18862Aspartame (e951)1-Methyl N-L-alpha-aspartyl-L-phenylalanateIns no.951SC 18862N-L-alpha-Aspartyl-L-phenylalanine 1-methyl ester3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl esterIns-9513-Amino-N-(alpha-methoxycarbonylphenethyl) succinamic acidNSC-758953
External database identifiers
- ChEBI:CHEBI:2877
- ChEMBL:CHEMBL171679
- EPA DTXSID:DTXSID0020107
- PubMed:40339580
- PubMed:38830726
- PubMed:37652922
- PubMed:37558167
- PubMed:33992720
- PubMed:32951320
- PubMed:31655124
- PubMed:25009784
- PubMed:23783067
- PubMed:23059992
- PubMed:23044217
- PubMed:23039008
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.