
Madecassic Acid
Madecassic acid is a pentacyclic triterpenoid that is ursane substituted by a carboxy group at position 28 and hydroxy groups at positions 2, 3, 6 and 23 (the 2alpha,3beta,6beta stereoisomer). It has a role as an antioxidant, an antibacterial agent, a hypoglycemic agent, an antineoplastic agent, an apoptosis inducer and a plant metabolite. It is a monocarboxylic acid, a pentacyclic triterpenoid and a tetrol. It is a conjugate acid of a madecassate. It derives from a hydride of an ursane. — ChEBI
- IUPAC name
- (1S,2R,4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
- Molecular formula
- C30H48O6
- Molecular weight
- 504.7 g/mol
- Exact mass
- 504.34508925 Da
- XLogP3
- 4.4
- Topological polar surface area
- 118.0 Ų
- Hydrogen-bond donors
- 5
- Hydrogen-bond acceptors
- 6
- Covalent units
- 1
- Defined stereocentres
- 13
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:73058
- ChEMBL:CHEMBL481854
- EPA DTXSID:DTXSID70939838
- PubMed:38527925
- PubMed:11408205
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.