Why does CAS 15545-48-9 appear in more than one EU cosmetic annex?

A substance identified by CAS 15545-48-9 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

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Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 15545-48-9 to screen it directly, then review every linked annex record and supplier document.

CAS 1 record

CAS 15545-48-9

Q: How do I use CAS 15545-48-9 for compliance screening?

Cross-reference CAS 15545-48-9 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 15545-48-9 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 15545-48-9

CAS 15545-48-9PubChem CID 27375

Chlortoluron

Chlorotoluron is a member of the class of phenylureas that is urea in which one of the nitrogens is substituted by two methyl groups while the other is substituted by a 3-chloro-4-methylphenyl group. A herbicide that is non-toxic to honeybees but moderately toxic to mammals, birds, earthworms and most aquatic organisms. It has a role as a herbicide, an agrochemical, a xenobiotic and an environmental contaminant. It is a member of phenylureas and a member of monochlorobenzenes. — ChEBI

IUPAC name: 3-(3-chloro-4-methylphenyl)-1,1-dimethylurea

Molecular formula: C10H13ClN2O
Molecular weight: 212.67 g/mol
Exact mass: 212.0716407 Da
XLogP3: 2.4
Topological polar surface area: 32.3 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 1
Covalent units: 1
Defined stereocentres: 0

Also known as

ChlorotoluronDicuranTolurexClortokemDikurin3-(3-Chloro-p-tolyl)-1,1-dimethylureaN'-(3-Chloro-4-methylphenyl)-N,N-dimethylureaUrea, N'-(3-chloro-4-methylphenyl)-N,N-dimethyl-

16 more reported names

N-(3-Chloro-4-methylphenyl)-N',N'-dimethylureaCGA 15646N,N-Dimethyl-N'-(3-chloro-4-methylphenyl)ureaSUW8L8G38AUrea, 3-(3-chloro-p-tolyl)-1,1-dimethyl-C 22423-(3-Chloro-4-methylphenyl)-1,1-dimethyl-ureaCHEBI:81981RefChem:125533239-592-21-(3-chloro-4-methylphenyl)-3,3-dimethylureaChlortoluron solution3-(3-Chlor-4-methylphenyl)-1,1-dimethylharnstoffHighuronChlortoluron [BSI]Caswell No. 216D

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:81981
ChEMBL:CHEMBL1900581
EPA DTXSID:DTXSID8052853
PubMed:39207506
PubMed:24920432
PubMed:22819367
PubMed:22590578
PubMed:22363586
PubMed:22278807
PubMed:22273262
PubMed:22261222
PubMed:22218326
PubMed:22196587
PubMed:22078267
PubMed:21909317

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 15545-48-9

1 total

Annex

Entry

1200

Chlorotoluron; (3-(3-Chloro-p-tolyl)-1,1-dimethylurea)

239-592-2

CMR

How CAS 15545-48-9 is used on this site

CAS 15545-48-9 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 15545-48-9 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 15545-48-9 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

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