Why does CAS 148477-71-8 appear in more than one EU cosmetic annex?

A substance identified by CAS 148477-71-8 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

How do I check if my formula contains a substance with CAS 148477-71-8?

Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 148477-71-8 to screen it directly, then review every linked annex record and supplier document.

CAS 1 record

CAS 148477-71-8

Q: How do I use CAS 148477-71-8 for compliance screening?

Cross-reference CAS 148477-71-8 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 148477-71-8 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 148477-71-8

CAS 148477-71-8PubChem CID 177863

Spirodiclofen

Spirodiclofen is a dichlorobenzene, a gamma-lactone, an oxaspiro compound and an organochlorine acaricide. It is functionally related to a 1,3-dichlorobenzene. — ChEBI

IUPAC name: [3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl] 2,2-dimethylbutanoate

Molecular formula: C21H24Cl2O4
Molecular weight: 411.3 g/mol
Exact mass: 410.1051646 Da
XLogP3: 5.9
Topological polar surface area: 52.6 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

EnvidorBAJ-27403X7G31F5MXBAJ27403-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoateCHEBI:386393-(2,4-DICHLOROPHENYL)-2-OXO-1-OXASPIRO(4.5)DEC-3-EN-4-YL 2,2-DIMETHYLBUTANOATE3-(2,4-DICHLOROPHENYL)-2-OXO-1-OXASPIRO(4.5)DEC-3-EN-4-YL 2,2-DIMETHYLBUTYRATE

16 more reported names

Butanoic acid, 2,2-dimethyl-, 3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro(4.5)dec-3-en-4-yl esterRefChem:8888433-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro(4.5)dec-3-en-4-yl 2,2-dimethylbutanoate604-636-5Spirodiclofen [ISO]UNII-3X7G31F5MXHSDB 7940BAJ 2740Spirodiclofen (Standard)SPIRODICLOFEN [MI]C21H24Cl2O4HY-B0826RHY-B0826Tox21_301133CS-5165Spirodiclofen 1000 |Ig/mL in Acetone

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:38639
ChEMBL:CHEMBL2227839
EPA DTXSID:DTXSID6034928
PubMed:22980892
PubMed:22606098
PubMed:22447041
PubMed:22162774
PubMed:22102515
PubMed:22058828
PubMed:21788198
PubMed:21580092
PubMed:21539243
PubMed:21520486
PubMed:20579688
PubMed:20540074

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 148477-71-8

1 total

Annex

Entry

1620

Spirodiclofen (ISO); 3-(2,4-dichlorophenyl)-2-oxo- 1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutyrate

604-636-5

CMR

How CAS 148477-71-8 is used on this site

CAS 148477-71-8 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 148477-71-8 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 148477-71-8 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

The INCI Checker accepts ingredient names, CAS numbers and EC numbers. Check this CAS number directly, then verify the result against supplier specification sheets and every linked annex condition.

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