CAS 142880-36-2 — 0 EU Cosmetic Records

Chemical identity and properties

PubChem 2D chemical structure for CAS 142880-36-2

CAS 142880-36-2PubChem CID 132519

Ilomastat

Ilomastat is an N-acyl-amino acid obtained by formal condensation of the carboxy group of (2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoic acid with the amino group of N-methyl-L-tryptophanamide. A cell permeable broad-spectrum matrix metalloproteinase (MMP) inhibitor. It has a role as an antibacterial agent, an antineoplastic agent, a neuroprotective agent, an anti-inflammatory agent and an EC 3.4.24.24 (gelatinase A) inhibitor. It is a hydroxamic acid, a L-tryptophan derivative and a N-acyl-amino acid. — ChEBI

IUPAC name: (2R)-N'-hydroxy-N-[(2S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl]-2-(2-methylpropyl)butanediamide

Molecular formula: C20H28N4O4
Molecular weight: 388.5 g/mol
Exact mass: 388.21105539 Da
XLogP3: 0.9
Topological polar surface area: 123.0 Å²
Hydrogen-bond donors: 5
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 2

Also known as

GalardinGM6001GM 6001CS 610GM-6001CS-610I0403ML141(R)-N(sup 1)-Hydroxy-N-((S)-2-indol-3-yl-1-(methylcarbamoyl)ethyl)-2-isobutylsuccinamide

16 more reported names

(S-(R*,S*))-N(sup 4)-Hydroxy-N(sup 1)-(1H-indol-3-ylmethyl)-2-(methylamino)-2-oxoethyl)-2-(2-methylopropyl)butanediamideCHEBI:137236ilomastatum(2R)-N'-hydroxy-N-((2S)-3-(1H-indol-3-yl)-1-methylamino-1-oxopropan-2-yl)-2-(2-methylpropyl)butanediamide(2R)-N'-hydroxy-N-[(2S)-3-(1H-indol-3-yl)-1-methylamino-1-oxopropan-2-yl]-2-(2-methylpropyl)butanediamideRefChem:790596N'-hydroxy-N-((S)-2-indol-3-yl-1-(methylcarbamoyl)ethyl)-2-isobutylsuccinamide(2R)-N'-hydroxy-N-((1S)-2-(1H-indol-3-yl)-1-(methylcarbamoyl)ethyl)-2-(2-methylpropyl)butanediamideButanediamide, N4-hydroxy-N1-((1S)-1-(1H-indol-3-ylmethyl)-2-(methylamino)-2-oxoethyl)-2-(2-methylpropyl)-,(2R)-Illomastat(R)-N1-((S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl)-N4-hydroxy-2-isobutylsuccinamideIlomastat (GM6001, Galardin)Ilomastat [USAN]3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDEGalardin MPI(2R)-2-[2-(hydroxyamino)-2-oxo-ethyl]-N-[(1S)-1-(1H-indol-3-ylmethyl)-2-(methylamino)-2-oxo-ethyl]-4-methyl-pentanamide

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:137236
ChEMBL:CHEMBL19611
EPA DTXSID:DTXSID0046353
PubMed:35687819
PubMed:34626302
PubMed:30549224
PubMed:26908177
PubMed:26490843
PubMed:24555532
PubMed:23894327
PubMed:23525277
PubMed:23462309
PubMed:23047022
PubMed:22581348
PubMed:22155090

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 142880-36-2

0 total

No records found for this CAS number.

How CAS 142880-36-2 is used on this site

CAS 142880-36-2 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 0 EU annex records share this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 142880-36-2 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.