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CAS 131-11-3

CAS 131-11-3 matches 0 EU annex records across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 131-11-3
CAS 131-11-3PubChem CID 8554

Dimethyl Phthalate

Dimethyl phthalate is a methyl ester, a phthalate ester and a diester. — ChEBI

IUPAC name
dimethyl benzene-1,2-dicarboxylate
Molecular formula
C10H10O4
Molecular weight
194.18 g/mol
Exact mass
194.05790880 Da
XLogP3
1.6
Topological polar surface area
52.6 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

DIMETHYLPHTHALATEAvolinMipaxPalatinol MSolvanomSolvaroneFermineDimethyl o-phthalate
16 more reported names
RepeftalPhthalic acid dimethyl esterUnimoll DMDimethyl 1,2-benzenedicarboxylatePhthalsaeuredimethylester1,2-Benzenedicarboxylic acid, dimethyl esterDimethyl benzene-o-dicarboxylateENT 262dimethylphtalateDMF (insect repellant)Dimethyl benzeneorthodicarboxylateRCRA waste number U102Phtalate de dimethyle08X7F5UDJMNSC-15398Dimethylester kyseliny ftalove
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match8554

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
  • First Aid: (General first aid procedures); Eye: Irrigate promptly - If this chemical contacts the eyes, promptly wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention if any discomfort continues.; Skin: Wash regularly; Breathing: Respiratory support; Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately. Source: The National Institute for Occupational Safety and Health (NIOSH)
  • Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H242: Heating may cause a fire [Danger Self-reactive substances and mixtures; Organic peroxides]; H302: Harmful if swallowed [Warning Acute toxicity, oral]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P210, P234, P235, P240, P260, P261, P264, P270, P272, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P330, P333+P317, P362+P364, P363, P370+P378, P391, P403, P405, P410, P411, P420, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Note: This chemical does not meet GHS hazard criteria for 95.7% (1993 of 2082) of all reports. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 1993 of 2082 companies (only 4.3% companies provided GHS information). For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 2082 reports by companies from 15 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 1993 of 2082 reports by companies.; There are 14 notifications provided by 89 of 2082 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: NITE-CMC
  • GHS Hazard Statements: H320: Causes eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]; H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P261, P264+P265, P271, P273, P304+P340, P305+P351+P338, P319, P337+P317, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • GHS Hazard Statements: H320: Causes eye irritation [Warning Serious eye damage/eye irritation]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects] Source: NITE-CMC
  • Precautionary Statement Codes: P261, P264+P265, P271, P304+P340, P305+P351+P338, P319, P337+P317, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • GHS Hazard Statements: H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard] Source: Hazardous Substances Data Bank (HSDB)
  • Health Effects: Phthalate esters are endocrine disruptors. Animal studies have shown that they disrupt reproductive development and can cause a number of malformations in affected young, such as reduced anogenital distance (AGD), cryptorchidism, hypospadias, and reduced fertility. The combination of effects associated with phthalates is called 'phthalate syndrome’. (A2883) Source: Toxin and Toxin Target Database (T3DB)
  • Cosmetic Ingredient Review Finding(s): Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org Source: Cosmetic Ingredient Review (CIR)
  • Toxicity Summary: IDENTIFICATION AND USE: Dimethyl phthalate (DMP) is a pale yellow, or colorless, oily liquid (solid below 42 °F) with slight aromatic odor. It is used as plasticizer for nitrocellulose and cellulose acetate, resins, and in solid rocket propellants; lacquers; plastics; rubber; coating agents; safety glass; and molding powders. Formerly it was used as a repellant for flies on horses and cows, and as a leech repellant. DMP is not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses. HUMAN EXPOSURE AND TOXICITY: In man, dimethyl phthalate has caused skin irritation reactions and skin sensitization was induced in one individual. Repeated inhalation of the vapor irritated the nose and upper respiratory tract. If swallowed, DMP may cause irritation of the stomach, dizziness, and unconsciousness. In one fatal case of suicidal ingestion of a mixture containing dimethyl phthalate and ketone peroxides, the principal toxic symptoms were marked esophagitis, gastritis, and hemorrhage. Mortality of human sperm in vitro was reduced by 25% in cultures containing 0.4 mM DM Source: Hazardous Substances Data Bank (HSDB)
  • Toxicity Summary: Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expression. Some phthalates have also been shown to reduce the expression of insulin-like peptide 3 (insl3), an important hormone secreted by the Leydig cell necessary for development of the gubernacular ligament. Animal studies have shown that these effects disrupt reproductive development and can cause a number of malformations in affected young. (A2883) Source: Toxin and Toxin Target Database (T3DB)
  • Environmental Bioconcentration: The mean BCF of dimethyl phthalate in sheepshead minnows was 5.4, after 24 hr(1). Bluegill sunfish showed a bioconcentration factor of 57(2) which may be elevated because only carbon-14 was measured in the experiment and metabolites may be included in the measurement of the parent compound(SRC). The depuration half-life was between 1 and 2 days(2). According to a classification scheme(3), these measured BCFs suggest that bioconcentration in aquatic organisms is low to moderate(SRC). The mean BCF of dimethyl phthalate in brown shrimp was 4.7, after 24 hr(1). Bioaccumulation factors of 3.1 and 6.3 were measured in shrimp (Peneaus aztecus) following 1 day of exposure(4). BCFs of 0.14-0.57 were reported for dimethyl phthalate in water spinach (Ipomoea aquatica) grown under different conditions on sludge from waste water treatment plants in China(5). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), Koc values of 55-360(2-4), indicate that dimethyl phthalate is expected to have high to moderate mobility in soil(SRC). Volatilization of dimethyl phthalate from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 2.0X10-7 atm-cu m/mole(SRC), based upon its vapor pressure, 3.08X10-3 mm Hg(5), and water solubility, 4000 mg/L(6). Dimethyl phthalate is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(5). Biodegradation half-lives in contaminated soil ranging from 15 to 123 days(7) suggest that biodegradation is dependent on prior exposure and subsequent acclimation(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), a log Koc value of >5.2 measured in suspended solids(2), indicates that dimethyl phthalate is expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 2.0X10-7 atm-cu m/mole(SRC), derived from its vapor pressure, 3.08X10-3 mm Hg(4), and water solubility, 4000 mg/L(5). The hydrolysis half-life of dimethyl phthalate is estimated to be 3.2 yr under neutral conditions at 30 °C(6). However, at pH 9, the estimated half-lives are 11.6 and 25 days at 30 and 18 °C, respectively(7). According to a classification scheme(8), BCFs of 5.4 in sheepshead minnows(9) and 57 in bluegill sunfish(10), suggest bioconcentration in aquatic organisms is low to moderate(SRC). Biodegradation half-lives have been reported as 1-5 days in water/sediment environments and 2-12 days in water(11). Other studies saw complete removal of dimethyl phthalate in 8-11 days in river water, but only 20-32% degradation in seawater in 2 weeks(12). These studies indicate that biodegradation will occur(SRC). The half-life for direct photolysis in surface waters is estimated at Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), dimethyl phthalate, which has a vapor pressure of 3.08X10-3 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase dimethyl phthalate is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 28 days(SRC), calculated from its rate constant of 5.7X10-13 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Dimethyl phthalate contains chromophores that absorb at wavelengths >290 nm(4) and, therefore, may be susceptible to direct photolysis by sunlight(SRC). Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
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A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

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How CAS 131-11-3 is used on this site

CAS 131-11-3 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 0 EU annex records share this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 131-11-3 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.