
Ethidium Bromide
Ethidium bromide is the organic bromide salt of ethidium. It has a role as a geroprotector, an intercalator and a trypanocidal drug. It contains an ethidium. — ChEBI
- IUPAC name
- 5-ethyl-6-phenylphenanthridin-5-ium-3,8-diamine bromide
- Molecular formula
- C21H20BrN3
- Molecular weight
- 394.3 g/mol
- Exact mass
- 393.08406 Da
- Topological polar surface area
- 55.9 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 3
- Covalent units
- 2
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:4883
- ChEMBL:CHEMBL284328
- EPA DTXSID:DTXSID8025258
- PubMed:9921
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Color/Form: Dark red crystals from alcohol Source: Hazardous Substances Data Bank (HSDB)
- Color/Form: Maroon powder Source: Hazardous Substances Data Bank (HSDB)
- Density: 0.34 g/cm³ Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Flash Point: >100 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- LogP: log Kow= -0.38 /Estimated/ Source: Hazardous Substances Data Bank (HSDB)
- LogP: -1.1 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: 260-262 °C (decomposes) Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: 238-240 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Physical Description: Dark red solid; [Merck Index] Red to brown solid; [ICSC] Dark red powder; [Sigma-Aldrich MSDS] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: RED-TO-BROWN CRYSTALS. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Solubility: Solubility in 2-methoxyethanol is 20 mg/mL; ethanol, 2 mg/mL Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Soluble in 750 parts chloroform at 20 °C Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Soluble in 20 parts water at 20 °C Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Solubility in water, g/100ml at 20 °C: 5 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Vapor Pressure: 1.2X10-12 mm Hg at 25 °C /Estimated/ Source: Hazardous Substances Data Bank (HSDB)
- Vapor Pressure: Vapor pressure at 25 °C: negligible Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Exposure Routes: The substance can be absorbed into the body by inhalation and by ingestion. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H330: Fatal if inhaled [Danger Acute toxicity, inhalation]; H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Precautionary Statement Codes: P203, P260, P264, P270, P271, P280, P284, P301+P317, P304+P340, P316, P318, P320, P330, P403+P233, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Signal: Danger Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302 (97.1%): Harmful if swallowed [Warning Acute toxicity, oral]; H330 (85.3%): Fatal if inhaled [Danger Acute toxicity, inhalation]; H331 (26.5%): Toxic if inhaled [Danger Acute toxicity, inhalation]; H341 (97.1%): Suspected of causing genetic defects [Warning Germ cell mutagenicity] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P203, P260, P261, P264, P270, P271, P280, P284, P301+P317, P304+P340, P316, P318, P320, P321, P330, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 34 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
- GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H330: Fatal if inhaled [Danger Acute toxicity, inhalation]; H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
- Precautionary Statement Codes: P203, P260, P264, P270, P271, P280, P284, P301+P317, P304+P340, P316, P318, P320, P330, P403+P233, P405, and P501 (click each P-code to see the statement) Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
- Sources/Uses: Used in the determination of nucleic acids and as an antimicrobial (Trypanosoma); [Merck Index] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: Used as a DNA probe Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.