
Phenoxyacetic Acid
Phenoxyacetic acid is a monocarboxylic acid that is the O-phenyl derivative of glycolic acid. A metabolite of 2-phenoxyethanol, it is used in the manufacture of pharmaceuticals, pesticides, fungicides and dyes. It has a role as a plant growth retardant, an allergen, an Aspergillus metabolite and a human xenobiotic metabolite. It is a monocarboxylic acid and an aromatic ether. It is functionally related to a glycolic acid. It is a conjugate acid of a phenoxyacetate. — ChEBI
- IUPAC name
- 2-phenoxyacetic acid
- Molecular formula
- C8H8O3
- Molecular weight
- 152.15 g/mol
- Exact mass
- 152.047344113 Da
- XLogP3
- 1.3
- Topological polar surface area
- 46.5 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 3
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:8075
- ChEMBL:CHEMBL173521
- EPA DTXSID:DTXSID9025873
- PubMed:22867432
- PubMed:22536127
- PubMed:22529852
- PubMed:22462445
- PubMed:22448339
- PubMed:22342144
- PubMed:22065827
- PubMed:22065310
- PubMed:22058862
- PubMed:22018865
- PubMed:21916510
- PubMed:21835019
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Boiling Point: 545 °F at 760 mmHg (Decomposes) (NTP, 1992) Source: CAMEO Chemicals
- Boiling Point: 285.00 °C. @ 760.00 mm Hg Source: Human Metabolome Database (HMDB)
- Boiling Point: 285 °C Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- LogP: 1.34 Source: Human Metabolome Database (HMDB)
- Melting Point: 208 to 212 °F (NTP, 1992) Source: CAMEO Chemicals
- Melting Point: 98 - 99 °C Source: Human Metabolome Database (HMDB)
- Physical Description: Phenoxyacetic acid appears as light tan powder or white solid. (NTP, 1992) Source: CAMEO Chemicals
- Physical Description: Solid Source: Human Metabolome Database (HMDB)
- Physical Description: Colourless needle-like crystals; sour sweet odour Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: 1 to 5 mg/mL at 63 °F (NTP, 1992) Source: CAMEO Chemicals
- Solubility: 12 mg/mL at 10 °C Source: Human Metabolome Database (HMDB)
- Solubility: Slightly soluble in water; soluble in oils Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: Soluble at room temperature (in ethanol) Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
- Note: This chemical does not meet GHS hazard criteria for 2.5% (5 of 198) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302 (93.4%): Harmful if swallowed [Warning Acute toxicity, oral]; H315 (96.5%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (97%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (89.4%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 198 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 5 of 198 reports by companies.; There are 12 notifications provided by 193 of 198 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.