Guanosine
Guanosine is a purine nucleoside in which guanine is attached to ribofuranose via a beta-N9-glycosidic bond. It has a role as a fundamental metabolite. It is a purines D-ribonucleoside and a member of guanosines. It is functionally related to a guanine. — ChEBI
- IUPAC name
- 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
- Molecular formula
- C10H13N5O5
- Molecular weight
- 283.24 g/mol
- Exact mass
- 283.09166853 Da
- XLogP3
- -1.9
- Topological polar surface area
- 155.0 Ų
- Hydrogen-bond donors
- 5
- Hydrogen-bond acceptors
- 7
- Covalent units
- 1
- Defined stereocentres
- 4
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:16750
- ChEMBL:CHEMBL375655
- EPA DTXSID:DTXSID00893055
- PubMed:36878458
- PubMed:32941855
- PubMed:27592390
- PubMed:25174304
- PubMed:23094695
- PubMed:23088278
- PubMed:23070860
- PubMed:23067123
- PubMed:23060960
- PubMed:23047748
- PubMed:23019414
- PubMed:23000492
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- LogP: -1.9 Source: DrugBank
- LogP: -1.90 Source: Human Metabolome Database (HMDB)
- Melting Point: 239 dec °C Source: DrugBank
- Melting Point: 239 °C Source: Human Metabolome Database (HMDB)
- Physical Description: Solid Source: Human Metabolome Database (HMDB)
- Solubility: 700 mg/L (at 18 °C) Source: DrugBank
- Solubility: 0.7 mg/mL at 18 °C Source: Human Metabolome Database (HMDB)
- Note: This chemical does not meet GHS hazard criteria for 11.8% (10 of 85) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H301 (87.1%): Toxic if swallowed [Danger Acute toxicity, oral] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 85 reports by companies from 5 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 10 of 85 reports by companies.; There are 3 notifications provided by 75 of 85 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.