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CAS 113-48-4

CAS 113-48-4 matches 0 EU annex records across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 113-48-4
CAS 113-48-4PubChem CID 101008927

Mgk 264

N-Octyl bicycloheptene dicarboximide (MGK 264) is an ingredient in some common pesticides. It has no intrinsic pesticidal activity itself, but rather is a synergist enhancing the potency of pyrethroid ingredients. It is used in a variety of household and veterinary products — Toxin and Toxin Target Database (T3DB)

IUPAC name
(1R,2S,6R,7S)-4-(2-ethylhexyl)-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione
Molecular formula
C17H25NO2
Molecular weight
275.4 g/mol
Exact mass
275.188529040 Da
XLogP3
3.4
Topological polar surface area
37.4 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
4

Also known as

Caswell No. 613UNII-1B9RV7L76COctyl bicycloheptenedicarboximideHSDB 1745N-(2-ethylhexyl)-5-norbornene-2,3-dicarboxamideN-Octyl bicycloheptene dicarboximideEINECS 204-029-1EPA Pesticide Chemical Code 057001
16 more reported names
BRN 0025024N-2-Ethylhexyl bicycloheptenedicarboximideAI3-08184Carboximide5-21-10-00184 (Beilstein Handbook Reference)N-Octylbicyclo-(2.2.1)-5-heptene-2,3-dicarboximideEndomethylenetetrahydrophthalic acid, N-2-ethylhexylimideEndomethylenetetrahydrophthalic acid, N-2-ethylhexyl imideN-(2-Ethylhexyl)-8,9,10-trinorborn-5-ene-2,3-dicarboximideETHYLHEXYLBICYCLOHEPTENE DICARBOXIMIDEMGK 264 [HSDB]ENT-8184NSC-36678NSC-406879N-(2-ETHYLEXYL)-NORBORNENE DICARBOXIMIDERefChem:158472
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match101008927

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 2.5% (2 of 80) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H311 (50%): Toxic in contact with skin [Danger Acute toxicity, dermal]; H317 (43.8%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H332 (46.2%): Harmful if inhaled [Warning Acute toxicity, inhalation]; H411 (46.2%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P262, P264, P270, P271, P272, P273, P280, P302+P352, P304+P340, P316, P317, P321, P333+P317, P361+P364, P362+P364, P391, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 80 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 2 of 80 reports by companies.; There are 5 notifications provided by 78 of 80 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: Hazardous Substances Data Bank (HSDB)
  • GHS Hazard Statements: H311: Toxic in contact with skin [Danger Acute toxicity, dermal]; H401: Toxic to aquatic life [Hazardous to the aquatic environment, acute hazard]; H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: Hazardous Substances Data Bank (HSDB)
  • Precautionary Statement Codes: P262, P264, P270, P273, P280, P302+P352, P316, P321, P361+P364, P391, P405, and P501 (click each P-code to see the statement) Source: Hazardous Substances Data Bank (HSDB)
  • Toxicity Summary: IDENTIFICATION AND USE: MGK 264 is a very light, yellow colored liquid. It is used as a synergist for pyrethroids in aerosol sprays for household and veterinary use. HUMAN STUDIES: In vitro, MGK 264 treatment did not result in statistically significant and reproducible alterations in testosterone or estradiol production. MGK 264 was negative for estrogen receptor transcriptional activation in the test system. MGK 264 inhibited aromatase activity. ANIMAL STUDIES: MGK 264 caused acute eye irritation in rabbits. A 90-day rat inhalation toxicity study demonstrated that at the lowest dose tested, there were indications of metaplasia/hyperplasia and changes in the larynx. At higher doses, histopathology of the larynx revealed additional changes and more intense changes in the epithelium and throat. The liver is the target organ of MGK 264. Liver effects were noted in the adults in a rat chronic/oncogenicity study, a mouse chronic/oncogenicity study, a rat multi-generation reproduction study, and subchronic and chronic dog studies. The dog appeared to be the most sensitive species for liver alterations but these alterations were limited to slight to moderate brown pigment and circulating Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Bioconcentration: An estimated BCF of 130 was calculated in fish for MGK 264(SRC), using a log Kow of 3.7(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is high, provided the compound is not metabolized by the organism. Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), Koc values of 636 and 3106(2) indicate that MGK 264 is expected to have low to slight mobility in soil(SRC). Volatilization of MGK 264 from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 2.8X10-7 atm-cu m/mole(SRC), using a fragment constant estimation method(3). MGK 264 is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 1.8X10-5 mm Hg at 25 °C(4). Biodegradation of MGK 264 is expected to be slow based on an aerobic biodegradation half-life of 341 days in soil(2). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), Koc values of 636 and 3106(2) indicate that MGK 264 is expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 2.8X10-7 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). According to a classification scheme(5), an estimated BCF of 130(SRC), from its log Kow of 3.7(6) and a regression-derived equation(4), suggests the potential for bioconcentration in aquatic organisms is high. MGK 264 did not undergo hydrolysis after 30 days under environmental conditions (pH 5 to 9)(6). Based on an aerobic biodegradation half-life of 341 days in soil, MGK 264 is not expected to biodegrade in water(2). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), MGK 264, which has a vapor pressure of 1.8X10-5 mm Hg at 25 °C(2), will exist in both the vapor and particulate phases in the ambient atmosphere. Vapor-phase MGK 264 is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 3.9 hours(SRC), calculated from its rate constant of 9.9X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). The rate constant for the vapor-phase reaction of MGK 264 with ozone has been estimated as 2.0X10-16 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). This corresponds to an atmospheric half-life of about 1.4 hours at an atmospheric concentration of 7X10+11 ozone molecules per cu cm(4). Particulate-phase MGK 264 may be removed from the air by wet and dry deposition(SRC). MGK 264 does not absorb at wavelengths >275 nm(5) and, therefore, is not expected to be susceptible to direct photolysis by sunlight(SRC). Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

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CAS 113-48-4 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 0 EU annex records share this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

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