CAS 111-60-4PubChem CID 24762
Glycol monostearate
Polyoxyl 40 stearate is an octadecanoate ester composed of repeating 8-40 ethyleneoxy units. It is an ingredient used in cosmetics and beauty products primarily as a surfactant and emulsifier. It has a role as a nonionic surfactant, an emulsifier and a food emulsifier. It is a hydroxypolyether and an octadecanoate ester. — ChEBI
- IUPAC name
- 2-hydroxyethyl octadecanoate
- Molecular formula
- C20H40O3
- Molecular weight
- 328.5 g/mol
- Exact mass
- 328.29774513 Da
- XLogP3
- 7.8
- Topological polar surface area
- 46.5 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 3
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
Ethylene glycol monostearateGlycol stearateMonthybaseMonthyleParastarinIvoritSedetolProdhybase ethyl
16 more reported names
Prodhybas NClindrol SEGEmerest 2350Ethylene glycol stearateLipo EGMSEmpilan 2848OCTADECANOIC ACID, 2-HYDROXYETHYL ESTERUSAF KE-11STEARIC ACID, 2-HYDROXYETHYL ESTERStearic acid, monoester with ethylene glycolS 1510324G66D0ECHEBI:167626RefChem:1086082203-886-9926-608-4
External database identifiers
- ChEBI:CHEBI:167626
- ChEBI:CHEBI:32027
- ChEMBL:CHEMBL2355383
- EPA DTXSID:DTXSID5026881
- PubMed:18717575
- PubMed:1680169
Evidence from additional scientific databases
NIH PubChem PUG-View
Exact identifier match24762
Attributed physical-property, hazard, environmental and use annotations.
- Color/Form: CREAM-COLORED SOFT, WAXY OR PASTY SOLID @ 25 °C Source: Hazardous Substances Data Bank (HSDB)
- Flash Point: MYRJ 45: 500 °F OC Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: MP: 30-34 °C /POLYETHYLENE GLYCOL 400 MONOSTEARATE USP XVI/ Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: 60.00 to 61.00 °C. @ 760.00 mm Hg Source: Human Metabolome Database (HMDB)
- Odor: FAINT FATTY ODOR Source: Hazardous Substances Data Bank (HSDB)
- Physical Description: Dry Powder; Other Solid; Large Crystals; Liquid; Liquid Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Light tan solid; [Hawley] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Solubility: POLYETHYLENE GLYCOL ESTERS AND ETHERS INCR THE WATER SOLUBILITY OF TYROTHRICIN. Source: Hazardous Substances Data Bank (HSDB)
- Solubility: SOL IN CARBON TETRACHLORIDE, PETROLEUM BENZIN, CHLOROFORM, ETHER; SLIGHTLY SOL IN ALCOHOL; INSOL IN WATER /POLYETHYLENE GLYCOL 400 MONOSTEARATE USP XVI/ Source: Hazardous Substances Data Bank (HSDB)
- Solubility: GENERALLY SOL OR DISPERSIBLE IN WATER Source: Hazardous Substances Data Bank (HSDB)
- Solubility: SOL IN TOLUENE, ACETONE, ETHER AND ETHANOL Source: Hazardous Substances Data Bank (HSDB)
- Note: This chemical does not meet GHS hazard criteria for 75.2% (357 of 475) of all reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H315 (18.9%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (19.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (17.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 475 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 357 of 475 reports by companies.; There are 10 notifications provided by 118 of 475 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Note: This chemical does not meet GHS hazard criteria for 87% (267 of 307) of all reports. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H319 (13%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 307 reports by companies from 3 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 267 of 307 reports by companies.; There are 2 notifications provided by 40 of 307 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Cosmetic Ingredient Review Finding(s): Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org Source: Cosmetic Ingredient Review (CIR)
- Consumer Uses: Surfactant (surface active agent); Plasticizer; Emulsifier Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Surfactant (surface active agent); Lubricating agent; Emulsifier; Plasticizer Source: EPA Chemical Data Reporting (CDR)
- Cosmetic Ingredient Review Link: CIR ingredient: Glycol Stearate Source: Cosmetic Ingredient Review (CIR)
- Cosmetic Ingredient Review Link: CIR ingredient: Glycol Stearate SE Source: Cosmetic Ingredient Review (CIR)
- Sources/Uses: Used as a surfactant, emulsifier (cosmetics, pharmaceuticals, textile finishes, defoamers, and baked goods), dye assistant, lubricant, and antistatic agent; Also used in dentifrice compositions and to make creams, lotions, ointments, and pharmaceutical preparations; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Textiles (Printing, Dyeing, or Finishing) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: SURFACTANT Source: Hazardous Substances Data Bank (HSDB)
- Uses: PEG 400 MONOSTEARATE USP XVI: IN PREPN OF CREAMS, LOTIONS, OINTMENTS & PHARMACEUTICAL PREPN WHICH ARE SOL IN WATER Source: Hazardous Substances Data Bank (HSDB)
- Uses: EMULSIFIER IN COSMETICS, PHARMACEUTICALS, TEXTILE FINISHES, DEFOAMERS; DYE ASSISTANT; LUBRICANT; ANTISTATIC AGENT Source: Hazardous Substances Data Bank (HSDB)
- Uses: IN SUNSCREEN COMPOSITIONS AS MOISTURIZING BASE Source: Hazardous Substances Data Bank (HSDB)
- Uses: For more Uses (Complete) data for POLYETHYLENE GLYCOL STEARATE (6 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.