CAS 111-57-9PubChem CID 27902
N-Stearoylethanolamine
N-(octadecanoyl)ethanolamine is an N-acylethanolamine 18:0 that is the ethanolamide of octadecanoic acid. It is functionally related to an octadecanoic acid. — ChEBI
- IUPAC name
- N-(2-hydroxyethyl)octadecanamide
- Molecular formula
- C20H41NO2
- Molecular weight
- 327.5 g/mol
- Exact mass
- 327.313729551 Da
- XLogP3
- 7.3
- Topological polar surface area
- 49.3 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 2
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
Stearic ethanolamideN-(Hydroxyethyl)stearamideOCTADECANAMIDE, N-(2-HYDROXYETHYL)-Monoethanolamine stearic acid amide03XV449Q24RefChem:825493Stearoyl ethanolamideN-(2-Hydroxyethyl)stearamide
16 more reported names
StearoylethanolamideStearamide MEAStearic monoethanolamideStearic acid monoethanolamideStearamylStearoyl-ethanolamineCycloamide SMComperlan HSStearoylmonoethanolamideStearoylethanolamineStearic ethylolamideMarlamid M 18Clindrol 200-MSLoramine S 280Stearic monoethanolamineStearoyl-EA
External database identifiers
- ChEBI:CHEBI:85299
- ChEMBL:CHEMBL171447
- EPA DTXSID:DTXSID9042178
- PubMed:22125609
- PubMed:20546561
- PubMed:20492349
- PubMed:20353771
- PubMed:19529773
- PubMed:19072766
- PubMed:18426496
- PubMed:18316044
- PubMed:16517404
- PubMed:15639235
- PubMed:15289450
- PubMed:14659458
Evidence from additional scientific databases
NIH PubChem PUG-View
Exact identifier match27902
Attributed physical-property, hazard, environmental and use annotations.
- Melting Point: 98.5 °C Source: Human Metabolome Database (HMDB)
- Physical Description: Large Crystals; Other Solid; Dry Powder Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Solid Source: Human Metabolome Database (HMDB)
- Note: This chemical does not meet GHS hazard criteria for 4.3% (12 of 281) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H315 (88.3%): Causes skin irritation [Warning Skin corrosion/irritation]; H318 (95.7%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H411 (37.4%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]; H412 (50.2%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264, P264+P265, P273, P280, P302+P352, P305+P354+P338, P317, P321, P332+P317, P362+P364, P391, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 281 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 12 of 281 reports by companies.; There are 5 notifications provided by 269 of 281 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Cosmetic Ingredient Review Conclusion: The CIR Expert Panel concluded that the ethanolamides listed subsequently are safe in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating. The Expert Panel cautioned that these ingredients should not be used in cosmetic products in which N-nitroso compounds may be formed...Stearamide MEA Source: Cosmetic Ingredient Review (CIR)
- Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)
- Consumer Uses: Surfactant (surface active agent) Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Stabilizing agent; Flow promoter; Emulsifier; Not Known or Reasonably Ascertainable; Surface modifier; Processing aids not otherwise specified; Surfactant (surface active agent); Opacifer Source: EPA Chemical Data Reporting (CDR)
- Cosmetic Ingredient Review Link: CIR ingredient: Stearamide MEA Source: Cosmetic Ingredient Review (CIR)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.