Skip to main content
CosIng Checker
CosIng Checker
EU cosmetic ingredients, restrictions and safety
Login
CAS 0 records

CAS 107-43-7

CAS 107-43-7 matches 0 EU annex records across Annex II–VI of Regulation 1223/2009.

Check this CAS numberBrowse annexes

Chemical identity and properties

PubChem 2D chemical structure for CAS 107-43-7
CAS 107-43-7PubChem CID 247

Betaine

Glycine betaine is the amino acid betaine derived from glycine. It has a role as a fundamental metabolite. It is an amino-acid betaine and a glycine derivative. It is a conjugate base of a N,N,N-trimethylglycinium. — ChEBI

IUPAC name
2-(trimethylazaniumyl)acetate
Molecular formula
C5H11NO2
Molecular weight
117.15 g/mol
Exact mass
117.078978594 Da
XLogP3
0.5
Topological polar surface area
40.1 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

glycine betaineoxyneurineTrimethylglycinelycineAbromineTrimethylglycocollGlycocoll betaineGlycylbetaine
16 more reported names
Rubrine C(Trimethylammonio)acetate2-(Trimethylammonio)AcetateJortaineBETAINE, ANHYDROUSBetaine anhydroustrimethylammonioacetateN,N,N-trimethylglycineTrimethylaminoacetic acidGlycine, trimethylbetaineLoramine AMB 13TrimethylaminoacetateAcidolGlykokollbetainMethanaminium, 1-carboxy-N,N,N-trimethyl-, inner saltN,N,N-trimethylammonioacetate
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:17750

glycine betaine

The amino acid betaine derived from glycine.

Formula
C5H11NO2
Average mass
117.148 g/mol
Monoisotopic mass
117.07898 Da
Formal charge
0
  • amino-acid betaine — is a (CHEBI:22860)
  • glycine derivative — is a (CHEBI:24373)
  • fundamental metabolite — has role (CHEBI:78675)
  • fundamental metabolite — has role (CHEBI:78675)
  • amino-acid betaine — is a (CHEBI:22860)
  • glycine derivative — is a (CHEBI:24373)
  • N,N,N-trimethylglycinium — is conjugate base of (CHEBI:41139)
Additional curated names
(trimethylammonio)acetate1-carboxy-N,N,N-trimethylmethanaminium inner salt2-N,N,N-trimethylammonio acetateabromineacidolBetBetaineN,N,N-trimethylammonioacetateGlycine betaineN,N,N-TrimethylglycineTrimethylaminoacetateTrimethylammonioacetate(trimethylammoniumyl)acetatetrimethylglycinetrimethylglycocoll
Cross-references from this source
  • CAS: 107-43-7 — KEGG COMPOUND
  • CAS: 107-43-7 — ChemIDplus
  • CAS: 107-43-7 — NIST Chemistry WebBook
  • REGISTRY_NUMBER: 26434 — Gmelin
  • REGISTRY_NUMBER: 3537113 — Reaxys
  • MANUAL_X_REF: 347 — DrugCentral
  • MANUAL_X_REF: BET — PDBeChem
  • MANUAL_X_REF: BETAINE — MetaCyc
  • MANUAL_X_REF: C00007291 — KNApSAcK
  • MANUAL_X_REF: C00719 — KEGG COMPOUND
  • MANUAL_X_REF: C00719 — KEGG COMPOUND
  • MANUAL_X_REF: D07523 — KEGG DRUG
  • MANUAL_X_REF: HMDB0000043 — HMDB
  • MANUAL_X_REF: Trimethylglycine — Wikipedia
  • MANUAL_X_REF: YMDB01516 — YMDB

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2024-04-18. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match247

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 90.4% (274 of 303) of all reports. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 274 of 303 companies (only 9.6% companies provided GHS information). For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 303 reports by companies from 5 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 274 of 303 reports by companies.; There are 3 notifications provided by 29 of 303 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Cosmetic Ingredient Review Conclusion: The CIR Expert Panel concluded that the eleven alkyl betaines listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Betaine... Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)
  • Environmental Bioconcentration: An estimated BCF of 0.3 was calculated in fish for betaine(SRC), using a water solubility of 611,000 mg/L at 19.3 °C(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC), provided the compound is not metabolized by the organism(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 3(SRC), determined from a water solubility of 611,000 mg/L at 19.3 °C(2) and a regression-derived equation(3), indicates that betaine is expected to have very high mobility in soil(SRC). The estimated pKa of betaine, an inner salt, is 2.38(4). Volatilization of betaine from moist soil surfaces is not expected to be an important fate process(SRC) because ionic compounds do not volatilize. Betaine is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 1.4X10-8 mm Hg(SRC), determined from a fragment constant method(5). No information on the aerobic biodegradation of betaine was located; however, the mineralization of alkyl betaine surfactants is considerable (>60% BODT reached in 28-day screening tests(6,7)) indicating that it is likely that betaine is also readily mineralized(SRC). Betaine is expected to biodegrade under anaerobic conditions as well based on data indicating that it is removed during anaerobic sewage treatment(8). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 3(SRC), determined from a water solubility of 611,000 mg/L at 19.3 °C(2) and a regression-derived equation(3), indicates that betaine is not expected to adsorb to suspended solids and sediment(SRC). An estimated pKa of 2.38(4) indicates betaine, will exist entirely as an inner salt at pH values of 5 to 9 and therefore volatilization from water surfaces will not occur as ionic compounds do not volatilize. According to a classification scheme(5), an estimated BCF of 0.3(SRC), from its water solubility(2) and a regression-derived equation(6), suggests the potential for bioconcentration in aquatic organisms is low(SRC). No information on the aerobic biodegradation of betaine was located; however, the mineralization of alkyl betaine surfactants is considerable (>60% BODT reached in 28-day screening tests(7,8)) indicating that it is likely that betaine is also readily mineralized(SRC). Betaine is expected to biodegrade under anaerobic conditions as well based on data indicating that it is removed during anaerobic sewage treatment(9). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), betaine, which has an estimated vapor pressure of 1.4X10-8 mm Hg at 25 °C(SRC), determined from a fragment constant method(2), is expected to exist solely in the particulate phase in the ambient atmosphere. Particulate-phase betaine may be removed from the air by wet or dry deposition(SRC). Betaine does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(3). Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 107-43-7

0 total
No records found for this CAS number.

How CAS 107-43-7 is used on this site

CAS 107-43-7 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 0 EU annex records share this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 107-43-7 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.