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CAS 2 records

CAS 1064-48-8

CAS 1064-48-8 matches 2 EU annex records across Annex II–VI of Regulation 1223/2009.

Chemical identity and properties

PubChem 2D chemical structure for CAS 1064-48-8
CAS 1064-48-8PubChem CID 135442942

2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-3-(2-(4-nitrophenyl)diazenyl)-6-(2-phenyldiazenyl)-, sodium salt (1:?)

Amido Black 10B is an organic sodium salt resulting from the formal condensation of Amido Black 10B (acid form) with two equivalents of sodium hydroxide. It has a role as a histological dye. It contains a 4-amino-5-hydroxy-3-[(p-nitrophenyl)azo]-6-(phenylazo)-naphthalene-2,7-disulfonate. ChEBI

IUPAC name
disodium;4-amino-5-hydroxy-3-[(4-nitrophenyl)diazenyl]-6-phenyldiazenylnaphthalene-2,7-disulfonate
Molecular formula
C22H14N6Na2O9S2
Molecular weight
616.5 g/mol
Exact mass
616.00590696 Da
Topological polar surface area
273.0 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
14
Covalent units
3
Defined stereocentres
0

Also known as

4-Amino-5-hydroxy-3-((4-nitrophenyl)azo)-6-(phenylazo)naphthalene-2,7-disulphonic acid, sodium saltRefChem:446195280-105-8ACID BLACK 1Naphthol Blue BlackAmido Black 10BAcid black 28005-03-6
16 more reported names
Buffalo Black NBRC.I. Acid Black 1NIGROSINEAmidoschwarzAmido blackC.I. Acid Black 1, disodium saltAcidal Black 10BNaphthol Blue Black BAcidal Navy Blue 3BRAcid Blue BlackAcid Blue-BlackC.I. 20470Sandopel Blue PBoruta Black ASolar Blue BlackAcid Black H
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:86230

Amido Black 10B

An organic sodium salt resulting from the formal condensation of Amido Black 10B (acid form) with two equivalents of sodium hydroxide.

Formula
C22H14N6O9S2.2Na
Average mass
616.501 g/mol
Monoisotopic mass
616.00591 Da
Formal charge
0
  • organic sodium salt — is a (CHEBI:38700)
  • histological dye — has role (CHEBI:77178)
  • 4-amino-5-hydroxy-3-[(p-nitrophenyl)azo]-6-(phenylazo)-naphthalene-2,7-disulfonate — has part (CHEBI:86227)
  • histological dye — has role (CHEBI:77178)
  • organic sodium salt — is a (CHEBI:38700)
Additional curated names
disodium 4-amino-5-hydroxy-3-[(E)-(4-nitrophenyl)diazenyl]-6-[(E)-phenyldiazenyl]naphthalene-2,7-disulfonateAcid Black 1Buffalo Black NBRCI 20470C.I. Acid Black 1Naphthol blue blackNaphthol Blue Black
Cross-references from this source

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2015-06-29. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match135442942

Attributed physical-property, hazard, environmental and use annotations.

  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 283 of 315 companies Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 315 reports by companies from 4 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 283 of 315 reports by companies.; There are 2 notifications provided by 32 of 315 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Note: This chemical does not meet GHS hazard criteria for 100% (3 of 3) of all reports. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 3 reports by companies from 1 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 3 of 3 reports by companies.; There are 0 notifications provided by 0 of 3 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 1064-48-8

2 total
Annex
III
Entry
295

Acid Black 1

4-Amino-5-hydroxy-3-(4-nitrophenylazo)-6- (phenylazo)-2,7- naphthalenedisulfonic acid, disodium salt

Hair dye substance in non-oxidative hair dye products

EC
Max concentration
Annex
IV
Entry
46

CI 20470

Sodium 4-amino-5-hydroxy-3-[(4-nitrophenyl)azo]-6-(phenylazo)naphthalene-2,7-disulphonate
EC
Max concentration

How CAS 1064-48-8 is used on this site

CAS 1064-48-8 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 2 EU annex records share this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 1064-48-8 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

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A substance identified by CAS 1064-48-8 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

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A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

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