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CAS 106-65-0

CAS 106-65-0 matches 0 EU annex records across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 106-65-0
CAS 106-65-0PubChem CID 7820

Dimethyl Succinate

Dimethyl succinate is a colorless liquid. (USCG, 1999) — CAMEO Chemicals

IUPAC name
dimethyl butanedioate
Molecular formula
C6H10O4
Molecular weight
146.14 g/mol
Exact mass
146.05790880 Da
XLogP3
0.4
Topological polar surface area
52.6 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

DimethylsuccinateButanedioic acid, dimethyl esterSuccinic acid, dimethyl esterMethyl butanedioateFEMA No. 23961,4-dimethyl butanedioateButanedioic acid, 1,4-dimethyl esterNSC-52209
16 more reported names
914I2127JRRefChem:134276203-419-9Methyl succinateSuccinic acid dimethyl esterDBE-4 dibasic esterSuccinic acid-dimethyl esterDBE-4Dimethyl ester of succinic acidCH3OC(O)CH2CH2C(O)OCH3Dimethyl 2,3-butanedioatedimethyl butane-1,4-dioateCAS-106-65-0CCRIS 4803HSDB 5370EINECS 203-419-9
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:165393

Dimethyl succinate

Formula
C6H10O4
Average mass
146.142 g/mol
Monoisotopic mass
146.05791 Da
Formal charge
0
  • fatty acid methyl ester — is a (CHEBI:4986)
  • fatty acid methyl ester — is a (CHEBI:4986)
Additional curated names
dimethyl butanedioate
Cross-references from this source

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match7820

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
  • Note: This chemical does not meet GHS hazard criteria for 61.8% (730 of 1181) of all reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H319 (36.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 1181 reports by companies from 9 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 730 of 1181 reports by companies.; There are 7 notifications provided by 451 of 1181 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: NITE-CMC
  • GHS Hazard Statements: H227: Combustible liquid [Warning Flammable liquids]; H320: Causes eye irritation [Warning Serious eye damage/eye irritation]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]; H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P210, P260, P264+P265, P273, P280, P305+P351+P338, P319, P337+P317, P370+P378, P403, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Cosmetic Ingredient Review Finding(s): Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org Source: Cosmetic Ingredient Review (CIR)
  • Environmental Bioconcentration: An estimated BCF value of 1.1 was calculated for dimethyl succinate(SRC), using a measured log Kow of 0.35(1) and a recommended regression-derived equation(2). According to a classification scheme(3), this BCF value suggests that bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a recommended classification scheme(1), an estimated Koc value of 37(SRC), determined from a measured log Kow of 0.35(2) and a recommended regression-derived equation(3), indicates that dimethyl succinate is expected to have very high mobility in soil(SRC). Volatilization of dimethyl succinate from moist soil surfaces(SRC) is not expected to be important given an estimated Henry's Law constant of 6.4X10-8 atm-cu m/mole(SRC), using a fragment constant estimation method(4). Based upon a group contribution method for predicting the probability and rate of aerobic biodegradation(5), dimethyl succinate has been estimated to be highly biodegraded with complete biodegradation occurring over a period of weeks(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a recommended classification scheme(1), an estimated Koc value of 37(SRC), determined from a measured log Kow of 0.35(2) and a recommended regression-derived equation(3), indicates that dimethyl succinate is not expected to adsorb to suspended solids and sediment in water(SRC). Dimethyl succinate is not expected to volatilize from water surfaces(3,SRC) based on an estimated Henry's Law constant of 6.4X10-8 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). According to a classification scheme(5), an estimated BCF value of 1.1(3,SRC), from a measured log Kow(2), suggests that bioconcentration in aquatic organisms is low(SRC). Based upon a group contribution method for predicting the probability and rate of aerobic biodegradation(6), dimethyl succinate has been estimated to be highly biodegraded with complete biodegradation occurring over a period of weeks(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), dimethyl succinate, which has an estimated vapor pressure of 0.46 mm Hg at 25 °C(2,SRC), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase dimethyl succinate is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be about 14 days(3,SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Industry Uses: Adsorbent; Pigment; Adhesion/cohesion promoter; Intermediate; Processing aids, specific to petroleum production; Viscosity modifiers; Thickening agent; Not Known or Reasonably Ascertainable; Other; Solvent; Dispersing agent Source: EPA Chemical Data Reporting (CDR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 106-65-0

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How CAS 106-65-0 is used on this site

CAS 106-65-0 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 0 EU annex records share this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 106-65-0 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.