CAS 103-26-4PubChem CID 637520
Methyl Cinnamate
Methyl cinnamate is a methyl ester resulting from the formal condensation of methyl cinnamic acid with methanol. It is found naturally in the essential oils of Alpinia and Basil leaf oil, and widely used in the flavor and perfume industries. It has a role as an insect attractant, a volatile oil component, a flavouring agent, a fragrance and an anti-inflammatory agent. It is an alkyl cinnamate and a methyl ester. — ChEBI
- IUPAC name
- methyl (E)-3-phenylprop-2-enoate
- Molecular formula
- C10H10O2
- Molecular weight
- 162.18 g/mol
- Exact mass
- 162.068079557 Da
- XLogP3
- 2.6
- Topological polar surface area
- 26.3 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 2
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
Cinnamic acid methyl esterMethyl cinnamylateFEMA No. 2698CINNAMIC ACID, METHYL ESTERSemaSORB 9815533CV2ZCQLNSC-9411RefChem:817677
16 more reported names
203-093-8Methyl trans-cinnamateMethyl (E)-cinnamate1754-62-7Methyl 3-phenylpropenoateMethyl 3-phenylacrylateMethylcinnamatemethyl-3-phenylprop-2-enoatetrans-Methyl cinnamatemethyl (2E)-3-phenylprop-2-enoatetrans-Cinnamic acid methyl ester(E)-Methyl cinnamateMethyl trans-3-phenyl-2-propenoateMethyl 3-phenyl-2-propenoate(E)-3-Phenylacrylic acid methyl ester2-propenoic acid, 3-phenyl-, methyl ester, (2E)-
External database identifiers
- ChEBI:CHEBI:194138
- ChEBI:CHEBI:6857
- ChEMBL:CHEMBL55060
- EPA DTXSID:DTXSID5044314
- PubMed:29968805
- PubMed:15464616
- PubMed:7748198
Evidence from additional scientific databases
EMBL-EBI ChEBI
Exact identifier matchCHEBI:6857
methyl cinnamate
A methyl ester resulting from the formal condensation of methyl cinnamic acid with methanol. It is found naturally in the essential oils of Alpinia and Basil leaf oil, and widely used in the flavor and perfume industries.
- Formula
- C10H10O2
- Average mass
- 162.188 g/mol
- Monoisotopic mass
- 162.06808 Da
- Formal charge
- 0
- alkyl cinnamate — is a (CHEBI:17958)
- methyl ester — is a (CHEBI:25248)
- fragrance — has role (CHEBI:48318)
- volatile oil component — has role (CHEBI:27311)
- anti-inflammatory agent — has role (CHEBI:67079)
- flavouring agent — has role (CHEBI:35617)
- insect attractant — has role (CHEBI:24850)
- fragrance — has role (CHEBI:48318)
- volatile oil component — has role (CHEBI:27311)
- anti-inflammatory agent — has role (CHEBI:67079)
- flavouring agent — has role (CHEBI:35617)
- insect attractant — has role (CHEBI:24850)
- alkyl cinnamate — is a (CHEBI:17958)
- methyl ester — is a (CHEBI:25248)
- 18037211 Source: PubMed
- 18066606 Source: PubMed
- 22273148 Source: PubMed
- 24405047 Source: PubMed
- 25046838 Source: PubMed
- 25815070 Source: PubMed
- 28152405 Source: PubMed
- 28764029 Source: PubMed
- 29802834 Source: PubMed
- 34052086 Source: PubMed
- 35709502 Source: PubMed
- 7381745 Source: PubMed
- 841581 Source: PubMed
- IND20380578 Source: Agricola
- IND605813183 Source: Agricola
- IND606825425 Source: Agricola
Additional curated names
methyl 3-phenylprop-2-enoate3-phenyl-2-propenoic acid methyl ester3-phenylacrylic acid methyl estercinnamic acid methyl estercinnamic acid, methyl esterFEMA 2698methyl 3-phenyl-2-propenoatemethyl 3-phenylacrylatemethyl 3-phenylpropenoatemethyl cinnamylatemethyl ester of cinnamic acid
Cross-references from this source
- CAS: 103-26-4 — ChemIDplus
- CAS: 103-26-4 — NIST Chemistry WebBook
- REGISTRY_NUMBER: 386468 — Reaxys
- MANUAL_X_REF: C00053486 — KNApSAcK
- MANUAL_X_REF: C06358 — KEGG COMPOUND
- MANUAL_X_REF: FDB012001 — FooDB
- MANUAL_X_REF: HMDB0033833 — HMDB
- MANUAL_X_REF: Methyl_cinnamate — Wikipedia
Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2022-11-29. Retrieved: 2026-08-31. Open source record
NIH PubChem PUG-View
Exact identifier match637520
Attributed physical-property, hazard, environmental and use annotations.
- Boiling Point: 262-263 °C Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Physical Description: Liquid Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Solid with a fruity, balsamic odor like strawberries; mp = 36 deg C; [Merck Index] Light yellow crystals; mp = 36-38 deg C; [Sigma-Aldrich MSDS] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: Colourless crystalline mass, fruity balsamic odour Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: insoluble in water; soluble in oils Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: moderately soluble (in ethanol) Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Vapor Pressure: 0.04 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Note: This chemical does not meet GHS hazard criteria for 17.1% (298 of 1745) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H317 (82.9%): May cause an allergic skin reaction [Warning Sensitization, Skin] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P261, P272, P280, P302+P352, P321, P333+P317, P362+P364, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 1745 reports by companies from 6 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 298 of 1745 reports by companies.; There are 4 notifications provided by 1447 of 1745 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H317 (91.7%): May cause an allergic skin reaction [Warning Sensitization, Skin] Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 12 reports by companies from 2 notifications to the ECHA C&L Inventory.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Consumer Uses: Fragrance Source: EPA Chemical Data Reporting (CDR)
- Sources/Uses: Permitted for use as an inert ingredient in non-food pesticide products; [EPA] Used as a fragrance and flavoring agent; [Merck Index] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| EMBL-EBI ChEBI | Exact match | 2026-08-31 |
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.