
Resorcinol diglycidyl ether
Diglycidyl resorcinol ether is an aromatic ether. — ChEBI
- IUPAC name
- 2-[[3-(oxiran-2-ylmethoxy)phenoxy]methyl]oxirane
- Molecular formula
- C12H14O4
- Molecular weight
- 222.24 g/mol
- Exact mass
- 222.08920892 Da
- XLogP3
- 1.2
- Topological polar surface area
- 43.5 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 4
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:82318
- ChEMBL:CHEMBL1338613
- EPA DTXSID:DTXSID2020470
- PubMed:22029968
- PubMed:12748690
- PubMed:3768853
- PubMed:2276701
Evidence from additional scientific databases
EMBL-EBI ChEBI
Diglycidyl resorcinol ether
- Formula
- C12H14O4
- Average mass
- 222.240 g/mol
- Monoisotopic mass
- 222.08921 Da
- Formal charge
- 0
- aromatic ether — is a (CHEBI:35618)
- aromatic ether — is a (CHEBI:35618)
Cross-references from this source
- CAS: 101-90-6 — KEGG COMPOUND
- MANUAL_X_REF: C19228 — KEGG COMPOUND
Mapped by: Exact CAS cross-reference in the ChEBI compound record. Retrieved: 2026-08-31. Open source record
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Boiling Point: 342 °F at 0.8 mmHg (NTP, 1992) Source: CAMEO Chemicals
- Boiling Point: 172 °C @ 0.8 MM HG Source: Hazardous Substances Data Bank (HSDB)
- Boiling Point: at 0.0001kPa: 172 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Color/Form: STRAW-YELLOW LIQUID Source: Hazardous Substances Data Bank (HSDB)
- Density: 1.21 at 77 °F (NTP, 1992) - Denser than water; will sink Source: CAMEO Chemicals
- Density: SP GR: 1.21 @ 25 °C Source: Hazardous Substances Data Bank (HSDB)
- Density: Relative density (water = 1): 1.21 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Flash Point: 350 °F (NTP, 1992) Source: CAMEO Chemicals
- Flash Point: 113 °C Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Flash Point: 350 °F (OPEN CUP) Source: Hazardous Substances Data Bank (HSDB)
- Flash Point: 113 °C c.c. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: 98 to 115 °F (NTP, 1992) Source: CAMEO Chemicals
- Melting Point: 32 TO 33 °C Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: 32-33 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Odor: SLIGHT PHENOLIC ODOR Source: Hazardous Substances Data Bank (HSDB)
- Physical Description: Diglycidyl resorcinol ether appears as clear yellow or straw-yellow viscous liquid. Boiling point 172 °C; density 1.21 g / cm3. Possible carcinogen. Source: CAMEO Chemicals
- Physical Description: Liquid Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Yellow paste or liquid; [ICSC] Light yellow liquid; [MSDSonline] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: YELLOW PASTE OR LIQUID WITH CHARACTERISTIC ODOUR. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Refractive Index: INDEX OF REFRACTION: 1.541 @ 25 °C/D Source: Hazardous Substances Data Bank (HSDB)
- Solubility: less than 0.1 mg/mL at 64 °F (NTP, 1992) Source: CAMEO Chemicals
- Solubility: Miscible with most org resins Source: Hazardous Substances Data Bank (HSDB)
- Vapor Pressure: 40.7 mmHg at 77 °F ; 54.6 mmHg at 108 °F (NTP, 1992) Source: CAMEO Chemicals
- Vapor Pressure: 40.7 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Vapor Pressure: VAPOR PRESSURE LOW Source: Hazardous Substances Data Bank (HSDB)
- Viscosity: 500 CENTIPOISES (25 °C) Source: Hazardous Substances Data Bank (HSDB)
- IARC Carcinogenic Agent: Diglycidyl resorcinol ether Source: International Agency for Research on Cancer (IARC)
- IARC Carcinogenic Classes: Group 2B: Possibly carcinogenic to humans Source: International Agency for Research on Cancer (IARC)
- IARC Monographs: Volume 36: (1985) Allyl Compounds, Aldehydes, Epoxides and Peroxides; Volume Sup 7: Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42, 1987; 440 pages; ISBN 92-832-1411-0 (out of print); Volume 71: (1999) Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide (Part 1, Part 2, Part 3) Source: International Agency for Research on Cancer (IARC)
- Publication Year: 1999 Source: International Agency for Research on Cancer (IARC)
- Evaluation Year: 1998 Source: International Agency for Research on Cancer (IARC)
- Substance: Diglycidyl resorcinol ether (DGRE) Source: NTP Technical Reports
- NTP Technical Report: TR-257: Toxicology and Carcinogenesis Studies of Diglycidyl Resorcinol Ether (Technical Grade) (CASRN 101-90-6) In F344/N Rats and B6C3F1 Mice (Gavage Studies) (1986 ) Source: NTP Technical Reports
- Peer Review Date: 02/28/83 Source: NTP Technical Reports
- Conclusion for Male Rat: Clear Evidence Source: NTP Technical Reports
- Conclusion for Female Rat: Clear Evidence Source: NTP Technical Reports
- Conclusion for Male Mice: Clear Evidence Source: NTP Technical Reports
- Conclusion for Female Mice: Clear Evidence Source: NTP Technical Reports
- Exposure Routes: The substance can be absorbed into the body through the skin and by ingestion. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknow Source: CAMEO Chemicals
- Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H311: Toxic in contact with skin [Danger Acute toxicity, dermal]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]; H350: May cause cancer [Danger Carcinogenicity]; H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Precautionary Statement Codes: P203, P261, P262, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P351+P338, P316, P318, P321, P330, P332+P317, P333+P317, P337+P317, P361+P364, P362+P364, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Signal: Danger Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]; H311 (26.8%): Toxic in contact with skin [Danger Acute toxicity, dermal]; H312 (73.2%): Harmful in contact with skin [Warning Acute toxicity, dermal]; H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H341 (100%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]; H350 (26.8%): May cause cancer [Danger Carcinogenicity]; H351 (73.2%): Suspected of causing cancer [Warning Carcinogenicity]; H372 (22.6%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]; H373 (22.6%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]; H412 (94.6%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P203, P260, P261, P262, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P351+P338, P316, P317, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P361+P364, P362+P364, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 504 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: NITE-CMC
- GHS Hazard Statements: H350: May cause cancer [Danger Carcinogenicity] Source: NITE-CMC
- Precautionary Statement Codes: P203, P280, P318, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
- Signal: Warning Source: NITE-CMC
- GHS Hazard Statements: H315: Causes skin irritation [Warning Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]; H351: Suspected of causing cancer [Warning Carcinogenicity] Source: NITE-CMC
- Consumer Uses: Viscosity modifiers; Dispersing agent Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Viscosity modifiers; Intermediate; Dispersing agent Source: EPA Chemical Data Reporting (CDR)
- Sources/Uses: Used in epoxy resins and as a curing agent for polysulfide rubber; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Plastic Composites Manufacturing [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: Epoxy resins Source: Hazardous Substances Data Bank (HSDB)
- Uses: CURING AGENT FOR POLYSULFIDE RUBBER Source: Hazardous Substances Data Bank (HSDB)
- Uses: ... AS LIQUID EPOXY RESIN & AS REACTIVE DILUENT IN PRODN OF OTHER EPOXY RESINS. Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| EMBL-EBI ChEBI | Exact match | 2026-08-31 |
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.