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CAS 100-06-1

CAS 100-06-1 matches 0 EU annex records across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 100-06-1
CAS 100-06-1PubChem CID 7476

4'-Methoxyacetophenone

4-methoxyacetophenone is a member of the class of acetophenones that is acetophenone substituted by a methoxy group at position 4. It is a member of acetophenones and a monomethoxybenzene. — ChEBI

IUPAC name
1-(4-methoxyphenyl)ethanone
Molecular formula
C9H10O2
Molecular weight
150.17 g/mol
Exact mass
150.068079557 Da
XLogP3
1.7
Topological polar surface area
26.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

4-Methoxyacetophenone4-AcetylanisoleNovatoneLinarodin1-(4-methoxyphenyl)ethan-1-oneVananoteEthanone, 1-(4-methoxyphenyl)-4-Methoxyphenyl methyl ketone
16 more reported names
Acetophenone, 4'-methoxy-p-Methoxyphenyl methyl ketoneMethyl p-methoxyphenyl ketone4-MethoxyacetofenonFEMA No. 2005Anisyl, p-, methyl ketoneNSC 2095230IRH2BR587AI3-00227NSC-5601NSC-209523CHEBI:86567RefChem:517338202-815-9922-271-2Acetanisole
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:86567

4-methoxyacetophenone

A member of the class of acetophenones that is acetophenone substituted by a methoxy group at position 4.

Formula
C9H10O2
Average mass
150.177 g/mol
Monoisotopic mass
150.06808 Da
Formal charge
0
  • monomethoxybenzene — is a (CHEBI:25235)
  • acetophenones — is a (CHEBI:22187)
  • monomethoxybenzene — is a (CHEBI:25235)
  • acetophenones — is a (CHEBI:22187)
Additional curated names
1-(4-methoxyphenyl)ethan-1-one4-acetylanisole4-methoxyphenyl methyl ketoneacetanisole
Cross-references from this source
  • CAS: 100-06-1 — ChemIDplus
  • CAS: 100-06-1 — NIST Chemistry WebBook
  • REGISTRY_NUMBER: 742313 — Reaxys

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2015-07-21. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match7476

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]; H315 (12.7%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (10.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P264, P264+P265, P270, P280, P301+P317, P302+P352, P305+P351+P338, P321, P330, P332+P317, P337+P317, P362+P364, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 1856 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: Hazardous Substances Data Bank (HSDB)
  • GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H315: Causes skin irritation [Warning Skin corrosion/irritation] Source: Hazardous Substances Data Bank (HSDB)
  • Precautionary Statement Codes: P264, P270, P280, P301+P317, P302+P352, P321, P330, P332+P317, P362+P364, and P501 (click each P-code to see the statement) Source: Hazardous Substances Data Bank (HSDB)
  • Toxicity Summary: IDENTIFICATION AND USE: 4-Acetylanisole is a colorless to pale-yellow fused solid. It is used in perfumery (for floral odors), and flavoring. HUMAN EXPOSURE AND TOXICITY: Human systemic effects by inhalation: pulse rate increase without fall in blood pressure and blood pressure elevation. ANIMAL STUDIES: In an experiment using isolated bovine eyes, 4-acetylanisole did not show an ocular severe irritant or corrosive potential. Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Bioconcentration: An estimated BCF of 3 was calculated in fish for 4-acetylanisole (SRC), using a log Kow of 1.74(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), a log Koc value of 2.43(2) indicates that 4-acetylanisole is expected to have moderate mobility in soil(SRC). Volatilization of 4-acetylanisole from moist soil surfaces may be an important fate process(SRC) given an estimated Henry's Law constant of 8.9X10-6 atm-cu m/mole(3). 4-Acetylanisole is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 6.44X10-3 mm Hg at 25 °C(4). Biodegradation data in soil were not available(SRC, 2016). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), a log Koc value of 2.43(2) indicates that 4-acetylanisole is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces may be expected(3) based upon an estimated Henry's Law constant of 8.9X10-6 atm-cu m/mole(4). Using this Henry's Law constant and an estimation method(4), volatilization half-lives for a model river and model lake are 3 days and 42 days, respectively(SRC). According to a classification scheme(5), an estimated BCF of 3(SRC), from an estimated log Kow of 1.74(6) and a regression-derived equation(4), suggests the potential for bioconcentration in aquatic organisms is low. Biodegradation data in water were not available(SRC, 2016). An environmental half-life of 12 days was measured in sunlit surface waters at 40 °C(7). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 4-acetylanisole, which has a vapor pressure of 6.44X10-3 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase 4-acetylanisole is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 1 day(SRC), calculated from its rate constant of 2.05X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). 4-Acetylanisole contains chromophores that absorb at wavelengths >290 nm(4) and, therefore, may be susceptible to direct photolysis by sunlight(SRC). An environmental half-life of 12 days was measured in sunlit surface waters at 40 °C(5). Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 100-06-1

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How CAS 100-06-1 is used on this site

CAS 100-06-1 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 0 EU annex records share this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 100-06-1 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.