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Annex IV Entry 86 14/08/2020

1,2-Dihydroxyanthraquinone

CI 58000 / PIGMENT RED 83

1,2-Dihydroxyanthraquinone appears in Annex IV as a positive-list colorant entry for EU cosmetics.

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Permitted colorant— Annex IV, EU Regulation 1223/2009
Entry: 86

Chemical identity and properties

PubChem 2D chemical structure for CAS 72-48-0
CAS 72-48-0PubChem CID 6293

Alizarin

Alizarin is a dihydroxyanthraquinone that is anthracene-9,10-dione in which the two hydroxy groups are located at positions 1 and 2. It has a role as a chromophore, a dye and a plant metabolite. — ChEBI

IUPAC name
1,2-dihydroxyanthracene-9,10-dione
Molecular formula
C14H8O4
Molecular weight
240.21 g/mol
Exact mass
240.04225873 Da
XLogP3
3.2
Topological polar surface area
74.6 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

1,2-DihydroxyanthraquinoneMordant Red 111,2-Dihydroxy-9,10-anthracenedioneTurkey RedALIZARINEAlizarin BAlizarine Red1,2-Anthraquinonediol
16 more reported names
Alizarine BAlizarinaEljon MadderAlizarine NACAlizarine Red BAlizarine Red LAlizerine NACEljon Madder M1,2-Dihydroxy-9,10-anthraquinoneAlizarine 3BAlizarine L pasteAlizarine Red IPTurkey Red WAlizarine indicatorAlizarine Red B2Certiqual Alizarine
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Colour index or glossary

CI 58000 / PIGMENT RED 83

Chemical name

1,2-Dihydroxyanthraquinone

Chemical / IUPAC name

1,2-Dihydroxyanthraquinone

Color

Red

Regulatory information

Regulation

(EC) 2009/1223

See every entry this act set

Identified ingredients

Key data

CAS
72-48-0
EC
200-782-5
Annex
IV
Entry number
86

Inventory links for 1,2-Dihydroxyanthraquinone

Inventory Restriction reference
Ref 32780

CI 58000

CAS: 72-48-0
EC: 200-782-5
Inventory Identified ingredient
Ref 36575

PIGMENT RED 83

CAS: 104074-25-1; 72-48-0
EC: 200-782-5

Direct matches are limited for this record, so nearby entries from Annex IV are shown as well.

Annex IV 87
Nearby record in the same annex

CI 59040

CAS: 6358-69-6
EC: 228-783-6
Annex IV 84
Nearby record in the same annex

CI 50420

CAS: 8005-03-6
Annex IV 88
Nearby record in the same annex

CI 60724

CAS: 19286-75-0
EC: 242-939-0
Annex IV 83
Nearby record in the same annex

CI 50325

CAS: 6837-46-3; 6856-08-2
EC: -; 229-951-1
Annex IV 82
Nearby record in the same annex

CI 47005

CAS: 38615-46-2 ; 8004-92-0; 95193-83-2
EC: -; -; 305-897-5
Annex IV 90
Nearby record in the same annex

CI 60730

CAS: 4430-18-6
EC: 224-618-7
Annex IV 91
Nearby record in the same annex

CI 61565

CAS: 128-80-3
EC: 204-909-5
Annex IV 80
Nearby record in the same annex

CI 45430

CAS: 12227-78-0
EC: 240-474-8

What Annex IV means for 1,2-Dihydroxyanthraquinone

1,2-Dihydroxyanthraquinone is an approved colorant listed in Annex IV of EU Cosmetics Regulation 1223/2009. Only colorants on this positive list may be used to colour cosmetic products on the EU market.

Some colorants in Annex IV are restricted by product type — for example, prohibited from use around the eyes or in products applied to mucous membranes. Check the product type and conditions fields above before use.

This record is linked to 2 CosIng inventory ingredients for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Confirm colorant is used only in permitted product types listed above.
  • Record the Colour Index number and CAS identifier in the ingredient declaration.

Frequently asked questions

Yes. 1,2-Dihydroxyanthraquinone is included in Annex IV of EU Cosmetics Regulation 1223/2009 as a permitted colorant. Only colorants on this positive list may be used to colour cosmetic products in the EU. Check the product type conditions above for any use restrictions.

CAS 72-48-0 is the unique numerical identifier assigned to 1,2-Dihydroxyanthraquinone by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex IV record 1,2-Dihydroxyanthraquinone

This page summarizes one Annex IV record for 1,2-Dihydroxyanthraquinone from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex IV conditions for 1,2-Dihydroxyanthraquinone, but confirm any final regulatory decision against the current official annex wording and source files.

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